Iron: copper interactions: some new revelations

• Published in: Nutrition reviews Vol. 52; no. 9; pp. 311 - 315
• Main Author: Harris, E.D
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.1994; International Life Sciences Institute; Oxford University Press
• Subjects: Analytical, structural and metabolic biochemistry; Animals; Binding sites; Biochemistry; Biological and medical sciences; BLOOD CIRCULATION; Ceruloplasmin; Ceruloplasmin - metabolism; CIRCULACION SANGUINEA; CIRCULATION SANGUINE; COBRE; COPPER; Copper - physiology; CUIVRE; Diet; Enzymes; FER; Fundamental and applied biological sciences. Psychology; GENETICA; GENETICS; GENETIQUE; Hemoglobin; HIERRO; Humans; Hypotheses; Inorganic compounds; IRON; Iron - physiology; MEMBRANA; MEMBRANE; MEMBRANES; METABOLISM; METABOLISME; METABOLISMO; Metals; NUTRIENT NUTRIENT INTERACTIONS; nutrient transport; NUTRIENTES; NUTRIENTS; Nutrition; Nutritional Physiological Phenomena; Other biological molecules; Photosynthesis; physiology; Plasma; Proteins; Saccharomyces cerevisiae; SUBSTANCE NUTRITIVE; Yeast; Nutrition; Interaction; Iron; Metal; Trace element (nutrient); Review; Copper; Inorganic element
• ISSN: 0029-6643; 1753-4887
• DOI: 10.1111/j.1753-4887.1994.tb01462.x

Iron and copper show an uncommon but largely unexplained interdependence, the basis for which is being clarified in hemoglobin‐synthesizing cells, yeast, and photosynthetic microrgansims. The interactions of the two metals with membrane transport systems and genetic regulators are more apt to be cooperative than antagonistic.