内窥镜下经蝶筛径路视神经减压术联合激素及神经生长因子治疗短期外伤性视神经病变

目的:介绍内窥镜下经筛蝶径路视神经减压术治疗短期外伤性视神经病变的临床效果。 方法:回顾性研究151例首诊小于5 d的外伤性视神经病变患者,所有患者入院后用甲基强的松针治疗3d,其中117名患者激素治疗后视力无显著提高。术后对激素治疗后视力无显著提高患者局部和全身使用激素和神经生长因子。根据术前视力,患者分为A组(无光感组)和B组(有残余视力组)。 结果:117例激素治疗后视力无显著提高患者中,70例视力有提高,有效率为59.8%。 A组和B组有效率分别为44.8%和80.0%。 B 组有效率显著高于 A 组(χ2=14.781, P〈0.05)。 结论:内窥镜下经筛蝶径路视神经减压术联合激素...

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Bibliographic Details
Published in国际眼科杂志 Vol. 16; no. 11; pp. 1981 - 1987
Main Author 余波 龚灿 马颖洁 吴文灿
Format Journal Article
LanguageChinese
Published 温州医科大学附属眼视光医院,中国浙江省温州市,325027%417000中国湖南省娄底市中心医院眼科 2016
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Summary:目的:介绍内窥镜下经筛蝶径路视神经减压术治疗短期外伤性视神经病变的临床效果。 方法:回顾性研究151例首诊小于5 d的外伤性视神经病变患者,所有患者入院后用甲基强的松针治疗3d,其中117名患者激素治疗后视力无显著提高。术后对激素治疗后视力无显著提高患者局部和全身使用激素和神经生长因子。根据术前视力,患者分为A组(无光感组)和B组(有残余视力组)。 结果:117例激素治疗后视力无显著提高患者中,70例视力有提高,有效率为59.8%。 A组和B组有效率分别为44.8%和80.0%。 B 组有效率显著高于 A 组(χ2=14.781, P〈0.05)。 结论:内窥镜下经筛蝶径路视神经减压术联合激素和神经生长因子治疗短期外伤性神经病变可能是一种有效的治疗方法,术前有残余视力患者疗效好于无光感患者。然而,对于无光感患者也可能通过此治疗提高视力。
Bibliography:BoYu, CanGong, Ying-JieMa, Wen-CanWu (1Department of Orbital & Oculoplastic Surgery, Eye Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China 2 Department of Ophthalmology, Loudi Central Hospital, Loudi 417000, Hunan Province, China Correspondence to:Wen-Can Wu. Department of Orbital & Oculoplastic Surgery, Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.)
endoscopic trans- ethmosphenoid optic canal decompression;steroid;nerve growth factor
61-1419/R
AIM: To present the efficacy of Endoscopic trans -ethmosphenoid optic canal decompression ( ETOCD ) combined with steroid and nerve growth factor ( NGF ) therapy in patients with short - time traumatic optic neuropathy( TON) . METHODS:A retrospective analysis of 151 TON patients (151 eyes) were performed. Their first treatment were all initiated within 5 days of injury. All patients were treated with methylprednisolone for 3 days. There were 117 patients did not improve with methylprednisolone treatment were
ISSN:1672-5123
DOI:10.3980/j.issn.1672-5123.2016.11.01