Effect of ROS Inhalation on Systemic and Local Hemodynamics in Rats

The effects of inhalation of singlet oxygen mixture, dry and humidified ozone-oxygen mixture, and ozonated oils on heart rate variability as well as on the rate and control mechanisms of microcirculation were examined in rats. The most optimal were the responses of systemic and regional hemodynamics...

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Published inBulletin of experimental biology and medicine Vol. 161; no. 5; pp. 634 - 637
Main Authors Martusevich, A. K., Peretyagin, S. P., Martusevich, A. A., Peretyagin, P. V.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.09.2016
Springer
Springer Nature B.V
Subjects
Active oxygen
Administration, Inhalation
Animals
Biomedical and Life Sciences
Biomedicine
Cell Biology
Drug Evaluation, Preclinical
Heart rate
Heart Rate - drug effects
Internal Medicine
Laboratory Medicine
Microcirculation - drug effects
Ozone - administration & dosage
Pathology
Physiological aspects
Rats
Singlet Oxygen - administration & dosage
singlet oxygen
heart rate variability
microcirculation
ozone
reactive oxygen species
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Summary:The effects of inhalation of singlet oxygen mixture, dry and humidified ozone-oxygen mixture, and ozonated oils on heart rate variability as well as on the rate and control mechanisms of microcirculation were examined in rats. The most optimal were the responses of systemic and regional hemodynamics to inhalation of the gas produced by a generator of singlet oxygen and humidified ozone-oxygen mixtures. Singlet oxygen stabilized the cardiac rhythm and augmented microcirculation via activation of “internal” (endothelial and neurogenic) regulatory mechanisms.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-016-3473-4