Oncocytic Type Intraductal Papillary Mucinous Neoplasm of the Pancreas with Unusually Low Mucin Production Mimicking Intraductal Tubulopapillary Neoplasm: A Report of a Case Diagnosed by a Preoperative Endoscopic Biopsy

• Published in: Internal Medicine Vol. 56; no. 23; pp. 3183 - 3188
• Main Authors: Yoshida, Yukinari, Endo, Takao, Tanaka, Eiichi, Kikuchi, Takefumi, Akino, Kimishige, Mita, Hiroaki, Adachi, Yasuyo, Nakamura, Masahiro, Adachi, Yasushi, Ishii, Yoshifumi, Matsumoto, Joe, Hirano, Satoshi, Nitta, Takeo, Mitsuhashi, Tomoko, Kato, Yasuo
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.01.2017; Japan Science and Technology Agency
• Subjects: Biopsy; Case Report; Case reports; endoscopic biopsy; Endoscopy; Internal medicine; IOPNs; IPMNs; Medical instruments; Mimicry; Mucin; Mucous membrane; Neoplasia; oncocytic type; Pancreas; preoperative diagnosis; Tumors; endoscopic biopsy; IPMNs; preoperative diagnosis; IOPNs; oncocytic type
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.9053-17

We herein report the case of a 78-year-old woman with an intraductal tumor with scant mucin production in a moderately dilated main pancreatic duct that resembled an intraductal tubulopapillary neoplasm (ITPN) on imaging. An endoscopic transpapillary forceps biopsy enabled an accurate preoperative diagnosis of the tumor as an oncocytic type intraductal papillary mucinous neoplasm (IPMN) of the pancreas microscopically showing papillary growth consisting of oncocytic cells with a typical mucin expression profile, although with few intraepithelial lumina containing mucin. This is the first case of an oncocytic type IPMN mimicking an ITPN that was able to be diagnosed preoperatively.