Putative Novel Species of Genus Capnocytophaga, Capnocytophaga stomatis Bacteremia in a Patient with Multiple Myeloma after Direct Contact with a Cat

Capnocytophaga species are among the typical zoonotic pathogens causing infections following direct contact with animals. Recently, a putative novel species of zoonotic Capnocytophaga, Capnocytophaga stomatis, was reported. We herein report the first case of bacteremia caused by C. stomatis. A woman...

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Published inInternal Medicine Vol. 61; no. 14; pp. 2233 - 2237
Main Authors Shinohara, Koh, Tsuchido, Yasuhiro, Suzuki, Michio, Yamamoto, Kojiro, Okuzawa, Yasutaro, Imaoka, Koichi, Shimizu, Tsunehiro
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 15.07.2022
Japan Science and Technology Agency
Subjects
Ampicillin
Animals
Bacteremia
Bacteremia - complications
Bacteremia - drug therapy
Bites and Stings
Blood culture
Bortezomib
Capnocytophaga
Capnocytophaga stomatis
Case Report
cellulitis
Dexamethasone
Female
Fever
Genomes
Gram-Negative Bacterial Infections - complications
Gram-Negative Bacterial Infections - diagnosis
Gram-Negative Bacterial Infections - drug therapy
Humans
Immunocompromised hosts
Internal medicine
Multiple myeloma
Multiple Myeloma - complications
Patients
Species
Sulbactam
Whole genome sequencing
Zoonoses
whole genome sequencing
multiple myeloma
Capnocytophaga stomatis
cellulitis
bacteremia
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Summary:Capnocytophaga species are among the typical zoonotic pathogens causing infections following direct contact with animals. Recently, a putative novel species of zoonotic Capnocytophaga, Capnocytophaga stomatis, was reported. We herein report the first case of bacteremia caused by C. stomatis. A woman in her 80s with multiple myeloma who was receiving bortezomib and dexamethasone therapy was admitted to our hospital with a 2-day history of a fever and right calf redness. She was often licked by her cat. On a blood culture, thin, Gram-negative rods were detected, which were identified as C. stomatis by whole-genome sequencing. The patient was successfully treated with ampicillin-sulbactam treatment. Our case highlights the pathogenic potential of the putative novel Capnocytophaga, C. stomatis, in immunocompromised hosts.
Bibliography:ObjectType-Case Study-2
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Correspondence to Dr.　Koh Shinohara, shinoharakoh@kuhp.kyoto-u.ac.jp
ISSN:0918-2918
1349-7235
1349-7235
DOI:10.2169/internalmedicine.7947-21