Experimental Development of New Surgical Suturing Materials with Complex Biological Activities

New surgical suturing materials with complex biological activities (antibacterial and stimulating tissue regeneration) have been developed. In vitro studies demonstrated pronounced and prolonged (up to 10-12 days) antibacterial activity. Experiments on 108 male albino rats proved the positive effect...

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Published inBulletin of experimental biology and medicine Vol. 153; no. 3; pp. 409 - 413
Main Authors Mokhov, E. M., Homullo, G. V., Sergeev, A. N., Alexandrov, I. V.
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.07.2012
Springer
Springer Nature B.V
Subjects
Animals
Anti-Bacterial Agents - therapeutic use
Antibacterial agents
Biomedical and Life Sciences
Biomedicine
Cell Biology
Granulation Tissue - drug effects
Health aspects
Internal Medicine
Laboratory Medicine
Male
Pathology
Rats
Sutures
Wound Healing - drug effects
antibacterial activity
regeneration
suturing materials
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Summary:New surgical suturing materials with complex biological activities (antibacterial and stimulating tissue regeneration) have been developed. In vitro studies demonstrated pronounced and prolonged (up to 10-12 days) antibacterial activity. Experiments on 108 male albino rats proved the positive effect of the materials on the wound process: shortening of the inflammation period, more rapid transformation of the granulation tissue, more rapid epithelialization of the wound and its pronounced contraction.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-012-1728-2