Improvement of accommodation with anti-oxidant supplementation in visual display terminal users

• Published in: The Journal of nutrition, health & aging Vol. 16; no. 5; pp. 478 - 481
• Main Authors: Uchino, Yuichi, Uchino, M, Dogru, M, Fukagawa, K, Tsubota, K
• Format: Journal Article
• Language: English
• Published: Paris Springer-Verlag 01.05.2012; Springer; Springer Nature B.V
• Subjects: Accommodation, Ocular - drug effects; Adult; Age; Aging; Antioxidants; Antioxidants - therapeutic use; Biological and medical sciences; Clinical trials; Computer Terminals; Dietary Supplements; Double-Blind Method; eyes; Feeding. Feeding behavior; Female; females; Fundamental and applied biological sciences. Psychology; Geriatrics/Gerontology; Humans; Japan; Japanese people; Male; males; Medicine; Medicine & Public Health; Middle Aged; monitors (image display); Neurosciences; Nutrition; Ophthalmology; Primary Care Medicine; Quality of Life Research; Strabismus; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Visual acuity; Vitamin C; Vitamin E; Japan; Visual Display Terminal (VDT); accommodation; antioxidant supplements; Nutrition; Metabolic diseases; Supplementation; Antioxidant; Feeding
• ISSN: 1279-7707; 1760-4788
• DOI: 10.1007/s12603-012-0059-3

OBJECTIVE: To determine the antioxidant supplementation effect on accommodation among VDT users. DESIGN: A double blind randomized placebo controlled study. Registered under Clinical Trials.gov Identifier No. NCT00877201. PARTICIPANTS AND CONTROLS: Fourty right eyes of 40 healthy VDT users (30 females, 10 males, mean age: 43.8±2.8 years, range: 40–49 years). 20 subjects (15 females, 5 males; mean age: 44.0±2.7 years, range: 40–49 years). METHODS: Subjects were required to take an antioxidant supplement, 20 age and sex matched subjects (15 females, 5 males; mean age: 43.6±3.1 years, range: 40–49 years) were required to take placebo medication for 4 weeks. RESULTS: The mean of the change in accommodation power was significantly higher in the group receiving antioxidant supplements (0.20±0.50 Diopter(D)) compared to the placebo group (−0.12±0.48(D)) (p<0.05). CONCLUSIONS: Antioxidant supplementation was observed to improve accommodation in Japanese Visual Display Terminal (VDT) Users.