Presence of Foveal Bulge in Optical Coherence Tomographic Images in Eyes With Macular Edema Associated With Branch Retinal Vein Occlusion

• Published in: American journal of ophthalmology Vol. 157; no. 2; pp. 390 - 396.e1
• Main Authors: Hasegawa, Taiji, Ueda, Tetsuo, Okamoto, Masahiro, Ogata, Nahoko
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2014; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Cataracts; Company reports; Diabetic retinopathy; Eyes & eyesight; Female; Fovea Centralis - pathology; Humans; Macular Edema - etiology; Macular Edema - physiopathology; Male; Middle Aged; Ophthalmology; Pharmaceutical industry; Photoreceptors; Retinal Photoreceptor Cell Inner Segment - pathology; Retinal Photoreceptor Cell Outer Segment - pathology; Retinal Vein Occlusion - complications; Retrospective Studies; Tomography, Optical Coherence; Visual Acuity - physiology
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/j.ajo.2013.10.007

Purpose To determine whether a significant correlation exists between the presence of a bulge in the photoreceptor inner segment/outer segment (IS/OS) line and the best-corrected visual acuity (BCVA) in eyes with resolved macular edema associated with branch retinal vein occlusion (BRVO). Design Retrospective, observational case series. Methods We retrospectively reviewed the medical records of patients who had a complete resolution of macular edema and had an intact IS/OS line in the central fovea in the spectral-domain optical coherence tomographic (SDOCT) images. Thirty-one eyes with macular edema associated with BRVO (BRVO group) and 31 unaffected fellow eyes (control group) of 31 patients were evaluated. In normal eyes, the intact IS/OS line determined by SDOCT has a bulge at the central fovea, called the foveal bulge. The eyes in the BRVO group were classified by the presence or absence of foveal bulge, and the characteristics of the 2 groups were compared. Results A foveal bulge was present in 7 of 31 eyes in the BRVO group. The incidence of a foveal bulge was significantly lower in the BRVO group (22.6%) than in the control group (100%; P < .0001). All 7 eyes with foveal bulge had a decimal BCVA of ≥1.0 at the final visit. The incidence of a foveal bulge was significantly higher in eyes with BCVA of ≥1.0 (77.8%) than in the eyes with BCVA of <1.0 (0%; P < .0001). Conclusions The foveal bulge is a good marker of the functional properties of the fovea in eyes with resolved macular edema associated with BRVO.