Sufficient reliability of the behavioral and computational readouts of a probabilistic reversal learning task

• Published in: Behavior research methods Vol. 54; no. 6; pp. 2993 - 3014
• Main Authors: Waltmann, Maria, Schlagenhauf, Florian, Deserno, Lorenz
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.12.2022; Springer Nature B.V
• Subjects: Behavioral Science and Psychology; Cognition; Cognitive ability; Cognitive Psychology; Computational neuroscience; Humans; Psychology; Reproducibility of Results; Reversal Learning; Probabilistic reversal learning; Computational modeling; Reliability; Reinforcement learning; Hierarchical modeling
• ISSN: 1554-3528; 1554-351X; 1554-3528
• DOI: 10.3758/s13428-021-01739-7

Task-based measures that capture neurocognitive processes can help bridge the gap between brain and behavior. To transfer tasks to clinical application, reliability is a crucial benchmark because it imposes an upper bound to potential correlations with other variables (e.g., symptom or brain data). However, the reliability of many task readouts is low. In this study, we scrutinized the retest reliability of a probabilistic reversal learning task (PRLT) that is frequently used to characterize cognitive flexibility in psychiatric populations. We analyzed data from N  = 40 healthy subjects, who completed the PRLT twice. We focused on how individual metrics are derived, i.e., whether data were partially pooled across participants and whether priors were used to inform estimates. We compared the reliability of the resulting indices across sessions, as well as the internal consistency of a selection of indices. We found good to excellent reliability for behavioral indices as derived from mixed-effects models that included data from both sessions. The internal consistency was good to excellent. For indices derived from computational modeling, we found excellent reliability when using hierarchical estimation with empirical priors and including data from both sessions. Our results indicate that the PRLT is well equipped to measure individual differences in cognitive flexibility in reinforcement learning. However, this depends heavily on hierarchical modeling of the longitudinal data (whether sessions are modeled separately or jointly), on estimation methods, and on the combination of parameters included in computational models. We discuss implications for the applicability of PRLT indices in psychiatric research and as diagnostic tools.