The effects of cognitive behavioral therapy on health-related quality of life, anxiety, depression, illness perception, and in atrial fibrillation patients: a six-month longitudinal study

• Published in: BMC Psychology Vol. 11; no. 1; p. 431
• Main Authors: Minjie, Zheng, Zhijuan, Xie, Xinxin, Shi, Xinzhu, Bai, Shan, Qu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 07.12.2023; BioMed Central; BMC
• Subjects: Ablation; Anxiety; Anxiety - psychology; Anxiety - therapy; Atrial fibrillation; Atrial Fibrillation - psychology; Atrial Fibrillation - therapy; Behavior modification; Cardiac arrhythmia; Cardiovascular disease; Catheters; CBT; Cognitive Behavioral Therapy; Cognitive therapy; Depression; Depression - psychology; Depression - therapy; Dyspnea; Generalized anxiety disorder; Health surveys; Heart; Humans; Illness perception; Intervention; Longitudinal Studies; Mental depression; Mental disorders; Participation; Patients; Perception; Prospective Studies; Quality of Life; Questionnaires; Thoracic surgery; Treatment Outcome; China; Depression; Anxiety; Illness perception; CBT; Atrial fibrillation; Quality of life
• ISSN: 2050-7283; 2050-7283
• DOI: 10.1186/s40359-023-01457-z

Atrial fibrillation (AF) often leads to an impaired Health-Related Quality of Life (HRQoL) in many patients. Moreover, psychological factors such as depression, anxiety, and illness perception have been found to significantly correlate with HRQoL. This study aims to evaluate the long-term effectiveness of Cognitive Behavioral Therapy (CBT) in enhancing HRQoL and mitigating psychological distress among AF patients. Employing a prospective, open design with pseudo-randomization, this study encompassed pre-tests, post-treatment evaluations, and a 6-month follow-up. A total of 102 consecutive patients diagnosed with paroxysmal AF were initially enrolled. Out of these, 90 were assigned to two groups; one to receive a 10-week CBT treatment specifically focusing on anxiety, and the other to receive standard care. Outcome measures were evaluated using tools such as the Item Short Form Health Survey (SF-12), General Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), University of Toronto Atrial Fibrillation Severity Scale (AFSS), and Brief Illness Perception Questionnaire (BIPQ). These assessments were conducted at pre-treatment, post-treatment, and at the 6-month follow-up mark. We explored the effectiveness of CBT using Generalized Estimating Equations (GEE). Our analysis revealed a notable improvement in the CBT group relative to the control group. All metrics displayed consistent improvement across a 6-month duration. At the 6-month checkpoint, the CBT group exhibited a more favorable SF-12 Mental Component Score (MCS) (50.261 ± 0.758 vs. 45.208 ± 0.887, p < 0.001), reduced GAD-7 (4.150 ± 0.347 vs. 8.022 ± 0.423, p < 0.001), BIPQ (34.700 ± 0.432 vs. 38.026 ± 0.318, p < 0.001), and AFSS (9.890 ± 0.217 vs. 10.928 ± 0.218, p = 0.001) scores when compared to the TAU group. Conversely, the SF-12 PCS (44.212 ± 0.816 vs. 47.489 ± 0.960, p = 0.139) and PHQ-9 scores (8.419 ± 0.713 vs. 10.409 ± 0.741, p = 0.794) manifested no significant difference between the two groups. The findings suggest that CBT is effective in improving HRQoL and reducing psychological distress among patients with AF at 6 month follow-up. This highlights the potential benefits of integrating CBT into the therapeutic regimen for AF patients. Retrospectively registered with ClinicalTrials.gov (NCT05716828). The date of registration : 5 June 2023.