MICROBIAL TRANSFORMATION OF DAUNOMYCINONE BY STREPTOMYCES AUREOFACIENS B-96
Daunomycinone, aglycone of the anthracycline antibiotic daunomycin, was transformed by a washed mycelia of Streptomyces aureofaciens B-96 in a buffer solution containing sucrose; the obtained product, dihydrodaunomycinone(9-(1-hydroxyethyl)-7, 8, 9, 10-tetrahydro-6, 7, 9, 11- tetrahydroxy-4-methoxy-...
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Published in | Journal of antibiotics Vol. 29; no. 11; pp. 1199 - 1202 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Japan
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
01.01.1976
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Subjects | |
Online Access | Get full text |
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Summary: | Daunomycinone, aglycone of the anthracycline antibiotic daunomycin, was transformed by a washed mycelia of Streptomyces aureofaciens B-96 in a buffer solution containing sucrose; the obtained product, dihydrodaunomycinone(9-(1-hydroxyethyl)-7, 8, 9, 10-tetrahydro-6, 7, 9, 11- tetrahydroxy-4-methoxy-5, 12-naphthacenequinone), was identified by measuring basic physicochemical characteristics (IR, UV and visible spectra, mass spectra and NMR, optical rotation and m. p.). |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0021-8820 1881-1469 |
DOI: | 10.7164/antibiotics.29.1199 |