Editorial: Carotid revasculatization vs best medical management in symptomatic carotid artery disease

• Published in: Annals of the Indian Academy of Neurology Vol. 21; no. 3; pp. 171 - 172
• Main Author: Moonis, Majaz
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.07.2018; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Care and treatment; Carotid arteries; Carotid artery; Carotid artery diseases; Diagnosis; Health aspects; Neovascularization; Risk factors; Stroke; India
• ISSN: 0972-2327; 1998-3549
• DOI: 10.4103/aian.AIAN_156_18

The study demonstrated a 17% absolute risk reduction (ARR) in reducing recurrent stroke in patients with symptomatic carotid disease who underwent carotid endarterectomy (CEA) compared to best medical management, mainly aspirin and risk factor reduction. [4] Medical management of large artery atherosclerosis-related stroke management underwent a dramatic change with wider implementation of risk factor reduction strategies and introduction of HMG-CoA Reductase Inhibitors (statins), nonexistent at the time of the NASCET or ECST trials. [4] In this issue, the investigators at a large university teaching hospital in Hyderabad, India, report the results of best medical therapy (vascular risk factor reduction, high-dose statins, dual antiplatelet therapy for 3 months and blood pressure reduction to <140/90 mmHg versus carotid intervention in symptomatic carotid artery disease.