Effects of temperature and humidity on acute myocardial infarction hospitalization in a super-aging society

• Published in: Scientific reports Vol. 11; no. 1; p. 22832
• Main Authors: Higuma, Takumi, Yoneyama, Kihei, Nakai, Michikazu, Kaihara, Toshiki, Sumita, Yoko, Watanabe, Mika, Doi, Shunichi, Miyamoto, Yoshihiro, Yasuda, Satoshi, Ishibashi, Yuki, Izumo, Masaki, Tanabe, Yasuhiro, Harada, Tomoo, Ogawa, Hisao, Akashi, Yoshihiro J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.11.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4019; 704/106; Age Factors; Aged; Aged, 80 and over; Aging; Databases, Factual; Demography; Female; Heart attacks; High temperature; Hospitalization; Humanities and Social Sciences; Humans; Humidity; Incidence; Japan - epidemiology; Low temperature; Male; Middle Aged; multidisciplinary; Myocardial infarction; Myocardial Infarction - diagnosis; Myocardial Infarction - epidemiology; Patient Admission; Patients; Registries; Regression analysis; Risk Assessment; Risk Factors; Science; Science (multidisciplinary); Seasons; Temperature; Temperature effects; Time Factors; Weather; Japan
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-021-02369-x

Weather conditions affect the incidence of acute myocardial infarction (AMI). However, little is known on the association of weather temperature and humidity with AMI hospitalizations in a super-aging society. This study sought to examine this association. We included 87,911 consecutive patients with AMI admitted to Japanese acute-care hospitals between April 1, 2012 and March 31, 2015. The primary outcome was the number of AMI hospitalizations per day. Multilevel mixed-effects linear regression models were used to estimate the association of the average temperature and humidity, 1 day before hospital admission, with AMI hospitalizations, after adjusting for weather, hospital, and patient demographics.Lower temperature and humidity were associated with an increased number of AMI hospitalizations (coefficient − 0.500 [− 0.524 to − 0.474] per °C change, p  < 0.001 and coefficient − 0.012 [− 0.023 to − 0.001] per % change, p  = 0.039, respectively). The effects of temperature and humidity on AMI hospitalization did not differ by age and sex (all interaction p > 0.05), but differed by season. However, higher temperatures in spring (coefficient 0.089 [0.025 to 0.152] per °C change, p  = 0.010) and higher humidity in autumn (coefficient 0.144 [0.121 to 0.166] per % change, p  < 0.001) were risk factors for AMI hospitalization. Increased average temperatures and humidity, 1 day before hospitalization, are associated with a decreased number of AMI hospitalizations.