Cloning of DOG1, a quantitative trait locus controlling seed dormancy in Arabidopsis
Genetic variation for seed dormancy in nature is a typical quantitative trait controlled by multiple loci on which environmental factors have a strong effect. Finding the genes underlying dormancy quantitative trait loci is a major scientific challenge, which also has relevance for agriculture and e...
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Published in | Proceedings of the National Academy of Sciences - PNAS Vol. 103; no. 45; pp. 17042 - 17047 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
National Academy of Sciences
07.11.2006
National Acad Sciences |
Subjects | |
Online Access | Get full text |
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Summary: | Genetic variation for seed dormancy in nature is a typical quantitative trait controlled by multiple loci on which environmental factors have a strong effect. Finding the genes underlying dormancy quantitative trait loci is a major scientific challenge, which also has relevance for agriculture and ecology. In this study we describe the identification of the DELAY OF GERMINATION 1 (DOG1) gene previously identified as a quantitative trait locus involved in the control of seed dormancy. This gene was isolated by a combination of positional cloning and mutant analysis and is absolutely required for the induction of seed dormancy. DOG1 is a member of a small gene family of unknown molecular function, with five members in Arabidopsis. The functional natural allelic variation present in Arabidopsis is caused by polymorphisms in the cis-regulatory region of the DOG1 gene and results in considerable expression differences between the DOG1 alleles of the accessions analyzed. |
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Bibliography: | http://dx.doi.org/10.1073/pnas.0607877103 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Author contributions: L.B. and M.K. designed research; L.B., J.J., and C.J.H. performed research; L.B. analyzed data; and L.B. and M.K. wrote the paper. Contributed by Maarten Koornneef, September 14, 2006 Present address: Section of Molecular and Cellular Biology, College of Biological Science, University of California, One Shields Avenue, Davis, CA 95616. Present address: Department of Molecular Plant Physiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. |
ISSN: | 0027-8424 1091-6490 |
DOI: | 10.1073/pnas.0607877103 |