Superior Vena Cava Syndrome Due to Fibrosing Mediastinitis Histologically Identical to Xanthogranulomatous Pyelonephritis

• Published in: Internal Medicine Vol. 42; no. 1; pp. 56 - 59
• Main Authors: KOJIMA, Satoshi, SUMIYOSHI, Masataka, SUWA, Satoru, TAMURA, Hiroshi, SASAKI, Akitoshi, KOJIMA, Takahiko, MlNEDA, Yoriaki, Ohta, Hiroshi, MATSUMOTO, Michio, Nakata, Yasuro
• Format: Journal Article
• Language: English
• Published: Tokyo The Japanese Society of Internal Medicine 2003; Japanese Society of Internal Medicine
• Subjects: Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Diagnosis, Differential; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Fibrosis - pathology; Humans; inflammatory change; Mediastinitis - complications; Mediastinitis - diagnosis; Mediastinitis - pathology; Medical sciences; Middle Aged; Nephrectomy; pathogenesis; Pyelonephritis, Xanthogranulomatous - complications; Pyelonephritis, Xanthogranulomatous - diagnosis; Pyelonephritis, Xanthogranulomatous - pathology; Superior Vena Cava Syndrome - etiology; Human; Radiodiagnosis; Mediastinum; Pathogenesis; Cardiovascular disease; Surgical resection; Posterior mediastinum; Nuclear magnetic resonance imaging; Vascular disease; Case study; Treatment; Vena cava disease; Surgery; Fibrosis; inflammatory change; Medical imagery; Adult; Complication; Female; Computerized axial tomography; Diagnosis
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.42.56

We present herein a case of superior vena cava (SVC) syndrome caused by localized fibrosing mediastinitis (FM), which had histological features similar to xanthogranulomatous pyelonephritis (XGP). A 63-year-old womanpresented with facial swelling 5 months after undergoing right nephrectomy for XGP. Radiologic investigations of the chest confirmed the presence of SVC obstruction due to an intraluminal tumor. The histological features of the tumor were consistent with those of FM and were very similar to those of XGP. Although the pathogenesis of neither FM nor XGP is known, some pathogenic process of FM and XGP may be the same. (Internal Medicine 42: 56-59, 2003)