Concurrent alteration in inflammatory biomarker gene expression and oxidative stress: how aerobic training and vitamin D improve T2DM

• Published in: BMC complementary and alternative medicine Vol. 22; no. 1; p. 165
• Main Authors: Hoseini, Rastegar, Rahim, Hiwa Ahmed, Ahmed, Jalal Khdhr
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 22.06.2022; BioMed Central; BMC
• Subjects: 8-Hydroxydeoxyguanosine; Aerobic training; Aerobics; Albumin; Albumins; Alfacalcidol; analysis of variance; antioxidant activity; Antioxidants; Biomarkers; Blood; Blood glucose; blood serum; Blood sugar; Body composition; Body mass index; Body size; C-reactive protein; Calcifediol; Calciferol; Catalase; Clinical trials; complement; Cytokines; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Dietary supplements; Exercise; Fasting; Fitness training programs; Gene expression; Genes; Glucose; Glutathione; Glutathione peroxidase; Heart beat; Heart rate; Homeostasis; Hyperglycemia; Inflammation; Insulin; Insulin resistance; Interleukin 1; Interleukin 4; interleukin-1beta; Interleukins; Kinases; Leukocytes (mononuclear); malondialdehyde; mitogen-activated protein kinase; NF-κB protein; nitrites; noninsulin-dependent diabetes mellitus; Oxidative stress; Peripheral blood mononuclear cells; Peroxidase; peroxisome proliferator-activated receptor gamma; Peroxisome proliferator-activated receptors; Pharmaceutical industry; Physical fitness; placebos; Polymerase chain reaction; Protein kinase; Protein kinases; Proteins; Signaling pathway; Superoxide; Superoxide dismutase; t-test; Thiols; Training; transcription factor NF-kappa B; tumor necrosis factor-alpha; Tumor necrosis factor-TNF; Type 2 diabetes; Variance analysis; Vitamin D; Vitamin D supplementation; Vitamin deficiency; Iran; Germany; United States > US

Background Vitamin D (Vit D) supplementation and Aerobic Training (AT) exert several beneficial effects such as antioxidant and anti-inflammatory actions. The literature on the effects of AT and Vit D supplementation on the oxidative stress biomarkers and gene expression of inflammatory cytokines in...