An Improved Urethral Catheterization in Female Pigs： A Pilot Study

• Published in: Chinese medical journal Vol. 130; no. 15; pp. 1880 - 1881
• Main Authors: Li, Da-Peng, Zhang, Wen-Hao, Yang, Ming-Liang, Liu, Chang-Bin, Zhang, Xin, Cai, Chang, Li, Jian-Jun
• Format: Journal Article
• Language: English
• Published: China Medknow Publications and Media Pvt. Ltd 05.08.2017; Lippincott Williams & Wilkins Ovid Technologies; School of Rehabilitation Medicine, Capital Medical University, Beijing 100068, China; Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing 100068, China; Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China; Department of Spinal and Neural Function Reconstruction, Beijing Boai Hospital, China Rehabilitation Research Center, Beijing 100068, China; Medknow Publications & Media Pvt Ltd; Wolters Kluwer
• Subjects: Animal experimentation; Bladder; Bladder Colostomy or Centesis; Female Miniature Pig; Urethral Catheterization; Brain research; Catheters; Clinical Challenge; Experiments; Health aspects; Hogs; Hospitals; Intubation; Laboratory animals; Medical research; Medicine; Pediatrics; Rehabilitation; Research centers; Researchers; Surgery; Swine; Urinary catheterization; Urine; 动物实验; 动物种类; 尿道; 巴马小型猪; 改良; 毒理试验; 流动力学; 科学研究; Female Miniature Pig; Bladder Colostomy or Centesis; Urethral Catheterization
• ISSN: 0366-6999; 2542-5641; 2542-5641
• DOI: 10.4103/0366-6999.211540

With the popularity of urine flow dynamic monitoring and indwelling catheter technologies in animal experiments,the urethral catheterization has become a common technique in scientific research.The miniature pig is considered as one of the major animal species used in scientific research and is increasingly being used as an alternative to a dog or monkey as the nonrodent species of choice in the preclinical toxicological testing of pharmaceuticals.[1] Since there are three acute angles bending in the urethra of the male miniature pig,and the end of the penis head is cork-screw shaped,it is difficult to implement routine urethral catheterization in male miniature pigs.Currently,researchers usually implement bladder colostomies or dissections in male miniature pigs,while transurethral urethral catheterization can be implemented in female miniature pigs.According to the existing reports,implementing transurethral urethral catheterization in female miniature pigs is seldom seen.[2] We chose 3-month-old female Bama miniature pigs in our experiments and employ the following methods：first,use a ＂V＂-shaped platform with an angle of about 30° to the horizontal plane;second,utilize a pediatric laryngoscope for deep lighting;third,bend the lower limbs and press down to the ventral side.Satisfactory results through transurethral urethral catheterization were achieved in the end.