Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects

• Published in: The New England journal of medicine Vol. 357; no. 8; pp. 741 - 752
• Main Authors: Sjöström, C. David, Sjöström, Lars, Narbro, Kristina, Karason, Kristjan, Larsson, Bo, Wedel, Hans, Lystig, Ted, Sullivan, Marianne, Bouchard, Claude, Carlsson, Lena M.S, Carlsson, Björn, Bengtsson, Calle, Dahlgren, Sven, Gummesson, Anders, Jacobson, Peter, Karlsson, Jan, Lindroos, Anna-Karin, Lönroth, Hans, Näslund, Ingmar, Olbers, Torsten, Stenlöf, Kaj, Torgerson, Jarl, Ågren, Göran
• Format: Journal Article
• Language: English
• Published: Boston, MA Massachusetts Medical Society 23.08.2007
• Subjects: Bariatric Surgery; Biological and medical sciences; Body Mass Index; Cardiovascular disease; Cardiovascular Diseases; Cardiovascular Diseases - mortality; Case-Control Studies; Endocrinology and Diabetes; Endokrinologi och diabetes; Epidemiology; Female; Follow-Up Studies; Gastrointestinal surgery; General aspects; Humans; Male; Medical sciences; Middle Aged; Mortality; Multivariate Analysis; Obesity; Obesity - mortality; Obesity - surgery; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Factors; surgery; Sweden; Sweden - epidemiology; Weight control; Weight Loss; Sweden; Europe; Human; Medicine; Obesity; Mortality; Nutrition disorder; Bariatric surgery; Epidemiology; Nutritional status; Swedish
• ISSN: 0028-4793; 1533-4406; 1533-4406
• DOI: 10.1056/NEJMoa066254

The prospective, controlled Swedish Obese Subjects study enrolled 4047 subjects who either underwent bariatric surgery or received conventional treatment. The results of follow-up for up to 15 years suggest that bariatric surgery for severe obesity is associated with long-term weight loss and decreased overall mortality. The results suggest that bariatric surgery for severe obesity is associated with long-term weight loss and decreased overall mortality. In the United States from 1980 through 2004, the prevalence of obesity — defined as a body-mass index (BMI) (the weight in kilograms divided by the square of the height in meters) of 30 or more — doubled, rising to include more than 30% of the population. 1 , 2 The majority of large and long-term epidemiologic studies have indicated that obesity is associated with increased mortality. 3 – 9 The life expectancy of severely obese persons is reduced by an estimated 5 to 20 years. 10 Weight loss is known to be associated with improvement of intermediate risk factors for disease, 11 suggesting that weight . . .