Biodegradable Polymer Films with a Natural Antibacterial Extract as Novel Periodontal Barrier Membranes

• Published in: International journal of biomaterials Vol. 2019; no. 2019; pp. 1 - 7
• Main Authors: Tuzlakoglu, Kadriye, Gul Seker, Mine, Renkler, Nergis Zeynep, Ahi, Zehra Betul
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2019; Hindawi; John Wiley & Sons, Inc; Hindawi Limited; Wiley
• Subjects: Antimicrobial agents; Biodegradability; Biodegradation; Biomedical materials; Cell adhesion & migration; Collagen; Composite materials; Disruption; Ethanol; Fourier transforms; Melting points; Membranes; Molecular structure; Morphology; Periodontics; Polylactic acid; Polymer blends; Polymer films; Polymers; Polyvinyl alcohol; Propolis; Regeneration; Spectrum analysis; Tissue engineering; Netherlands
• ISSN: 1687-8787; 1687-8795
• DOI: 10.1155/2019/7932470

Biodegradable composite membranes containing propolis were produced from PCL/PLLA blends using a simple and low-cost solvent casting method, and subsequently their physicochemical, mechanical, and antibacterial properties were characterized. SEM analysis revealed that the addition of propolis has created honeycomb-like structures on the film surfaces. The flexibility of the films increased in the presence of propolis, which may provide ease of use during application. Propolis disrupted the organized structure of both polymers at the molecular level and caused decreases in the melting points. The films with propolis showed faster degradation in physiological conditions due to this molecular disruption. Moreover, the PLLA/PCL/propolis composite films exhibited remarkable antibacterial activities against S. aureus. Collectively, the data suggest that the produced films might be used as an alternative to exiting barrier membranes in guided tissue regeneration.