High validity of measuring the width and volume of medial meniscal extrusion three-dimensionally using an MRI-derived tibial model

• Published in: Journal of experimental orthopaedics Vol. 7; no. 1; pp. 1 - 10
• Main Authors: Watanabe, Goro, Hoshi, Kenji, Kurose, Yasuo, Gamada, Kazuyoshi
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 03.01.2020; Springer Nature B.V; Wiley
• Subjects: CT-derived models; Knee; Medial meniscus; Medicine; Medicine & Public Health; Morphology; Orthopedics; Osteophyte; Three-dimensional models; Tibial plateau; Osteophyte; CT-derived models; Tibial plateau; Three-dimensional models; Medial meniscus
• ISSN: 2197-1153; 2197-1153
• DOI: 10.1186/s40634-019-0216-2

Background Medial meniscal extrusion (MME) is an important marker of knee osteoarthritis (KOA) progression. The purposes of this study were: 1) to determine whether there are morphological differences between CT- and MRI-derived tibial plateau models; and 2) to determine whether measurement of MME volume and width using an MRI-derived tibial model is as accurate as measurements on a CT-derived tibial model. Methods This was a cross-sectional study that enrolled ten participants with medial KOA (Kellgren-Lawrence grade 1 to 3). Primary outcome was surface difference of the medial tibial plateau between CT- and MRI-derived models. Furthermore, volume and cross-sectional area of the medial tibial plateau were compared between CT- and MRI-derived models. Measurements of MME volume and width were compared between CT- and MRI-derived tibial models. Results Minimal and maximal surface differences of the medial tibial plateau between the CT- and MRI-derived models were − 0.15 [− 0.44, 0.14] mm (mean [95% confidence interval]) and 0.24 [− 0.09, 0.57] mm, respectively. There were no significant differences in volume and cross-sectional area of the medial tibial plateau between CT- and MRI-derived tibial models. The MME volumes measured on CT- and MRI-derived models were 942.6 [597.7, 1287.6] mm 3 and 916.2 [557.9, 1274.6] mm 3 , respectively ( p  = 0.938). The MME widths measured on CT- and MRI-derived models were 4.2 [1.9, 6.5] mm and 4.5 [2.2, 6.9] mm, respectively ( p  = 0.967). Conclusions CT- and MRI-derived models of the medial tibial plateau did not show significant morphological differences. Both CT- and MRI-derived tibia can be used as a reference to measure MME in early-to-moderate medial KOA.