Guidelines for the Nomenclature of the Human Heat Shock Proteins

The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines for the nomenclature of the human HSP families, HSPH (HSP110), HSPC (HSP90), HSPA (HSP70), DNAJ (HSP40), a...

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Bibliographic Details
Published inCell stress & chaperones Vol. 14; no. 1; pp. 105 - 111
Main Authors Kampinga, Harm H., Hageman, Jurre, Vos, Michel J., Kubota, Hiroshi, Tanguay, Robert M., Bruford, Elspeth A., Cheetham, Michael E., Chen, Bin, Hightower, Lawrence E.
Format Journal Article
LanguageEnglish
Published Dordrecht Cell Stress Society International 01.01.2009
Springer Netherlands
Springer Nature B.V
Subjects
Animals
Biochemistry
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cell Biology
Chaperonins
Chaperonins - classification
Chaperonins - genetics
Family members
Family names
Genes
Heat shock proteins
Heat-Shock Proteins - classification
Heat-Shock Proteins, Small - classification
HSP110 Heat-Shock Proteins - classification
HSP40 Heat-Shock Proteins - classification
HSP70 Heat-Shock Proteins - classification
HSP90 Heat-Shock Proteins - classification
Human genome
Humans
Immunology
Mice
Molecular Chaperones - classification
Molecular Chaperones - genetics
Neurosciences
Proteins
Pseudogenes
Short Communication
Terminology
Terminology as Topic
Nomenclature
Human heat shock proteins
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Summary:The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines for the nomenclature of the human HSP families, HSPH (HSP110), HSPC (HSP90), HSPA (HSP70), DNAJ (HSP40), and HSPB (small HSP) as well as for the human chaperonin families HSPD/E (HSP60/HSP10) and CCT (TRiC). The nomenclature is based largely on the more consistent nomenclature assigned by the HUGO Gene Nomenclature Committee and used in the National Center of Biotechnology Information Entrez Gene database for the heat shock genes. In addition to this nomenclature, we provide a list of the human Entrez Gene IDs and the corresponding Entrez Gene IDs for the mouse orthologs.
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ObjectType-Instructional Material/Guideline-1
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ISSN:1355-8145
1466-1268
DOI:10.1007/s12192-008-0068-7