Protective effect of Carthamus tinctorius L. seed on oxidative stress and cognitive impairment induced by chronic alcohol consumption in mice

Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning...

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Published inFood science and biotechnology Vol. 27; no. 5; pp. 1475 - 1484
Main Authors Choi, Seung Hak, Lee, Ah Young, Park, Chan Hum, Shin, Yu Su, Cho, Eun Ju
Format Journal Article
LanguageEnglish
Published Singapore Springer Singapore 01.10.2018
Springer Nature B.V
한국식품과학회
Subjects
Acetaldehyde
Acetylcholinesterase
alcohol abuse
alcohol drinking
Alcohol use
Alcoholic beverages
Alcohols
Apoptosis
brain
Brain damage
Brain injury
Carthamus tinctorius
Chemistry
Chemistry and Materials Science
cognition
Cognitive ability
cognitive disorders
Dementia
Dementia disorders
enzyme activity
Food Science
inflammation
Kidneys
Lipid peroxidation
Lipids
Liver
memory
Mice
neurons
Nitric oxide
Nutrition
Object recognition
Oral administration
Oxidative stress
Pattern recognition
Peroxidation
protective effect
식품과학
Oxidative stress
Alcohol
Cognition
L. seed
Dementia
Carthamus tinctorius L. seed
Online AccessGet full text
ISSN1226-7708
2092-6456
2092-6456
DOI10.1007/s10068-018-0472-4

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Abstract Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and Carthamus tinctorius L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcohol-treated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia.
AbstractList Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcohol-treated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia.
Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and Carthamus tinctorius L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcohol-treated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia.
Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and Carthamus tinctorius L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcohol-treated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia.
Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and Carthamus tinctorius L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcoholtreated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia. KCI Citation Count: 14
Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and Carthamus tinctorius L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcohol-treated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia.Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol consumption and accumulates in the body to induce oxidative stress, apoptosis, and inflammation in neuronal cells, which results in learning and cognitive decline. In the present study, C57BL/N mice were orally administered alcohol (16%) and Carthamus tinctorius L. seed (CTS) (100 and 200 mg/kg/day). Behavioral experiments showed that memory and cognitive abilities were significantly higher in the CTS groups than the alcohol-treated control group in the T-maze test, novel object recognition test, and Morris water maze test. In addition, CTS inhibited alcohol-induced lipid peroxidation and nitric oxide production in the brain, kidney, and liver. Moreover, alcohol increased acetylcholinesterase activity in the brain, but this was significantly decreased by the administration of CTS. Therefore, CTS may play role in the prevention of alcohol-related dementia.
Author Lee, Ah Young
Cho, Eun Ju
Choi, Seung Hak
Park, Chan Hum
Shin, Yu Su
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  organization: Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration
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Cites_doi 10.1093/oxfordjournals.jbchem.a022368
10.1016/j.drugalcdep.2004.02.004
10.3390/ijms10010292
10.1016/0003-2697(79)90738-3
10.1016/S0301-0082(98)00091-4
10.1046/j.1471-4159.1994.63051855.x
10.1016/j.jamda.2017.09.013
10.3109/07853890008998828
10.1016/S0165-3806(02)00279-1
10.1016/j.bbr.2009.05.016
10.1016/j.alcohol.2013.12.001
10.1371/journal.pone.0055839
10.1006/ccog.1997.0319
10.1016/0166-2236(85)90010-4
10.1111/j.1530-0277.2006.00181.x
10.1523/JNEUROSCI.2947-12.2012
10.1111/j.1530-0277.2007.00450.x
10.1007/s11064-008-9884-5
10.1046/j.1532-5415.2001.49085.x
10.1111/j.1530-0277.1998.tb03653.x
10.1037/h0058118
10.1016/S0140-6736(05)70276-2
10.3892/etm.2016.3455
10.1515/tnsci-2017-0024
10.1016/0741-8329(95)02019-5
10.1073/pnas.1230907100
10.1016/j.freeradbiomed.2008.08.030
10.1142/S0192415X18500015
10.1111/j.1750-3639.2004.tb00079.x
10.1042/bj2680579
10.1016/S0149-7634(01)00041-0
10.1002/jnr.10208
10.1016/0076-6879(90)86135-I
10.1016/j.coph.2004.06.011
10.1097/01.ALC.0000156185.39073.D2
10.1016/j.jep.2013.12.003
10.1016/j.alcohol.2007.10.006
10.1016/j.neuroscience.2013.03.042
10.1155/2011/213286
10.1016/0165-0270(84)90007-4
10.3390/molecules23020481
10.1016/S0271-5317(01)00293-7
10.1186/1742-2094-5-10
10.1007/s12640-009-9083-4
10.1016/S0006-8993(99)01529-2
10.1007/978-3-7091-9350-1_13
10.1007/s00221-013-3818-4
10.1142/S0192415X16500130
10.1007/s11064-010-0155-x
10.1007/s00204-003-0465-8
10.1017/S146114571000060X
10.1248/cpb.45.1910
10.3177/jnsv.50.32
10.1016/j.jep.2010.10.029
10.1155/2012/465897
10.7326/0003-4819-120-3-199402010-00009
10.1007/s00213-012-2779-9
10.1016/j.neuropharm.2009.11.002
10.1038/nprot.2006.205
10.1080/13556219772570
10.1016/0140-6736(93)92185-V
10.1016/S0026-895X(25)08977-1
10.1016/S0022-3565(25)22244-3
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Keywords Oxidative stress
Alcohol
Cognition
L. seed
Dementia
Carthamus tinctorius L. seed
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한국식품과학회
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References Kang, Chang, Park (CR34) 1999; 4
Guo, Li (CR20) 2017; 8
Huang, Zhang, Chen (CR29) 2016; 12
Guerri (CR19) 1998; 22
Balduini, Costa (CR4) 1989; 250
Friedman (CR16) 2010
Morris (CR45) 1984; 11
Lee, Choi, Kim, Ganapathi, Udayakumar, Kim (CR40) 2009; 10
Tiwari, Chopra (CR66) 2012; 224
Thomas, Rockwood (CR65) 2001; 49
Halliwell, Gutteridge (CR21) 1985; 8
Herrera, Yague, Johnsen-Soriano, Bosch-Morell, Collado-Morente, Muriach, Romero, Garcia-Verdugo (CR24) 2003; 100
Asari, Mohd Ismail, Mohd Yusof (CR2) 2013; 6
Moon, Back, Kim, Jeon, Lee, Choi (CR44) 2001; 21
Tiwari, Kuhad, Chopra (CR68) 2009; 203
Qin, He, Hanes, Pluzarev, Hong, Crews (CR52) 2008; 18
Lowenstein, Dinerman, Synder (CR41) 1994; 120
Seo, Kim, Kwak, Jeon, Ku, Lee, Moon, Choi (CR58) 2000; 33
Jensen, Pakkenberg (CR31) 1993; 342
Wang, Chen, Tang, Wang, Li, Zhang (CR73) 2014; 151
Holownia, Ledig, Mapoles, Ménez (CR27) 1996; 13
Smith, Aragon, Amit (CR61) 1997; 2
Wang, Liu, Zhang, Li, Yang, Zhang, Gong, Han, Jia (CR74) 2018; 23
Gerridzen, Hertogh, Depla, Veenhuizen, Verschuur, Joling (CR17) 2018; 19
Montgomery (CR42) 1952; 45
Sakamura, Terayama, Kawakatsu, Ichihara, Saito (CR56) 1980; 44
Kril, Halliday (CR38) 1999; 58
Room, Babor, Rehm (CR55) 2005; 365
Schmidt, Warner, Nakane, Forstermann, Murad (CR57) 1992; 41
Jun, Ha, Kim, Jang, Kim, Lee, Kim, Seo, Lee, Lee, Chang (CR32) 2011; 133
Quertemont, Grant, Correa, Arizzi, Salamone, Tambour, Aragon, McBride, Rodd, Goldstein, Zaffaroni, Li, Pisano, Diana (CR53) 2005; 29
Cho, Choi, Choi, Lee (CR8) 2004; 50
Koop (CR37) 2006; 29
Harper, Matsumoto (CR23) 2005; 5
Jamal, Ameno, Miki, Tanaka, Ohkubo, Kinoshita (CR30) 2010; 35
Hiramatsu, Takahashi, Komatsu, Kido, Kasahara (CR25) 2014; 34
Seyedabadi, Fakhfouri, Ramezani, Mehr, Rahimian (CR59) 2014; 232
Zhang, Nagatsu, Watanabe, Sakakibara, Okuyama (CR78) 1997; 45
Draper, Hadley (CR13) 1990; 186
Climent, Pascual, Renau-Piqueras, Guerri (CR10) 2002; 68
Tiwari, Chopra (CR67) 2013; 244
Bae, Shim, Park, Lee, Chang, Choi (CR3) 2002; 11
Epstein (CR14) 1997; 21
Grant, Dawson, Stinson, Chou, Dufour, Pickering (CR18) 2004; 74
Cohen, Tong, Wands, de la Monte (CR11) 2007; 31
Esmaeili, Sonboli, Kanani, Sadeghi (CR15) 2009; 3
Niess, DickHuth, Northoff, Fehrenbach (CR47) 1999; 5
Tong, Longato, Nguyen, Chen, Spaisman, Monte (CR70) 2011; 2011
Haorah, Ramirez, Floreani, Gorantla, Morsey, Persidsky (CR22) 2008; 45
Zhang, Tian, Tang, Chen, Bian, Wang, Lu (CR79) 2016; 44
Cho, Park, Yoon, Choi, Ha (CR9) 2006; 38
Bevins, Besheer (CR5) 2006; 1
Kim, Oh, Lee, Lee, Choi (CR36) 2007; 16
Kavitha, Damodara Reddy, Paramahamsa, Akhtar, Varadacharyulu (CR35) 2008; 42
Olney, Tenkova, Dikranian, Qun, Labruyere, Ikonomidou (CR49) 2002; 133
Hou, Aboukhatwa, Lei, Manaye, Khan, Luo (CR28) 2010; 58
Ozbek (CR50) 2012; 2012
Croxson, Browning, Gaffan, Baxter (CR12) 2012; 32
Shaw, Jayatilleke (CR60) 1990; 268
Montoliu, Valles, Renau-Piqueras, Guerii (CR43) 1994; 63
Wu, Cederbaum (CR76) 2003; 27
Chen, Luo (CR7) 2016; 17
Song, Ra, Kim, Jung, Kim, Kang, Kang, Yeon, Kim, Lee, Shin, Park, Kim (CR62) 2002; 19
Yu, Chen, Wang, Kuang, Liu, Zhang, Du (CR77) 2013; 8
Tiwari, Kuhad, Chopra (CR69) 2010; 13
Kalmijn (CR33) 2000; 4
Roh, Sun, Oh, Lee, Oh, Kim (CR54) 1999; 8
Holownia, Ledig, Brszko, Ménez (CR26) 1999; 833
CR63
Nakamura, Iwahashi, Furukawa, Ameno, Kinoshita, Ijiri, Sekine, Suzuki, Iwata, Minabe, Mori (CR46) 2003; 77
Arendt (CR1) 1994
Lalonde (CR39) 2002; 26
Takii, Hayashi, Hiroma, Chiba, Kawashima, Zhang, Nagatsu, Sakakibara, Onozaki (CR64) 1999; 125
Zimatkin, Pronko, Vasiliou, Gonzalez, Deitrich (CR80) 2006; 30
Buhot, Martin, Segu (CR6) 2000; 32
Park, Lee, Kim, Seong, Jang, Cho, Choi, Kwon, Kim, Lee, Yokozawa, Shin (CR51) 2018; 46
Wagner, Zhou, Goodlett (CR72) 2014; 38
Woolf (CR75) 1997; 6
Ohkawa, Ohishi, Yagi (CR48) 1979; 95
Vallés, Blanco, Pascual, Guerri (CR71) 2004; 14
V Tiwari (472_CR67) 2013; 244
C Guerri (472_CR19) 1998; 22
SJ Bae (472_CR3) 2002; 11
DR Koop (472_CR37) 2006; 29
SL Vallés (472_CR71) 2004; 14
RA Bevins (472_CR5) 2006; 1
JL Wagner (472_CR72) 2014; 38
V Tiwari (472_CR69) 2010; 13
MS Jun (472_CR32) 2011; 133
T Takii (472_CR64) 1999; 125
HH Draper (472_CR13) 1990; 186
Z Guo (472_CR20) 2017; 8
AC Cohen (472_CR11) 2007; 31
KD Moon (472_CR44) 2001; 21
MA Esmaeili (472_CR15) 2009; 3
IJ Gerridzen (472_CR17) 2018; 19
J Haorah (472_CR22) 2008; 45
CJ Lowenstein (472_CR41) 1994; 120
M Epstein (472_CR14) 1997; 21
K Nakamura (472_CR46) 2003; 77
HJ Seo (472_CR58) 2000; 33
H Ohkawa (472_CR48) 1979; 95
W Balduini (472_CR4) 1989; 250
B Halliwell (472_CR21) 1985; 8
WJ Huang (472_CR29) 2016; 12
JJ Kril (472_CR38) 1999; 58
MA Asari (472_CR2) 2013; 6
VS Thomas (472_CR65) 2001; 49
X Wang (472_CR74) 2018; 23
YS Lee (472_CR40) 2009; 10
GH Kang (472_CR34) 1999; 4
EO Kim (472_CR36) 2007; 16
V Tiwari (472_CR66) 2012; 224
M Seyedabadi (472_CR59) 2014; 232
Y Hou (472_CR28) 2010; 58
KC Montgomery (472_CR42) 1952; 45
V Tiwari (472_CR68) 2009; 203
Joseph Friedman (472_CR16) 2010
AM Niess (472_CR47) 1999; 5
M Jamal (472_CR30) 2010; 35
E Climent (472_CR10) 2002; 68
A Holownia (472_CR27) 1996; 13
M Tong (472_CR70) 2011; 2011
HL Zhang (472_CR78) 1997; 45
R Morris (472_CR45) 1984; 11
L Yu (472_CR77) 2013; 8
HR Song (472_CR62) 2002; 19
BF Grant (472_CR18) 2004; 74
SH Cho (472_CR8) 2004; 50
G Chen (472_CR7) 2016; 17
D Wu (472_CR76) 2003; 27
L Qin (472_CR52) 2008; 18
C Montoliu (472_CR43) 1994; 63
S Kalmijn (472_CR33) 2000; 4
SH Cho (472_CR9) 2006; 38
E Quertemont (472_CR53) 2005; 29
PL Croxson (472_CR12) 2012; 32
BR Smith (472_CR61) 1997; 2
GB Jensen (472_CR31) 1993; 342
Y Wang (472_CR73) 2014; 151
NJ Woolf (472_CR75) 1997; 6
E Ozbek (472_CR50) 2012; 2012
DG Herrera (472_CR24) 2003; 100
A Sakamura (472_CR56) 1980; 44
S Shaw (472_CR60) 1990; 268
HH Schmidt (472_CR57) 1992; 41
LL Zhang (472_CR79) 2016; 44
T. Arendt (472_CR1) 1994
R Room (472_CR55) 2005; 365
C Harper (472_CR23) 2005; 5
SM Zimatkin (472_CR80) 2006; 30
JW Olney (472_CR49) 2002; 133
G Kavitha (472_CR35) 2008; 42
JS Roh (472_CR54) 1999; 8
CH Park (472_CR51) 2018; 46
MC Buhot (472_CR6) 2000; 32
M Hiramatsu (472_CR25) 2014; 34
472_CR63
R Lalonde (472_CR39) 2002; 26
A Holownia (472_CR26) 1999; 833
References_xml – volume: 125
  start-page: 910
  year: 1999
  end-page: 915
  ident: CR64
  article-title: Serotonin derivative, N-(p-coumaroyl)serotonin, isolated from safflower ( L.) oil cake augments the proliferation of normal human and mouse fibroblasts in synergy with basic fibroblast growth factor (FGF) of epidermal growth factor (EGF)
  publication-title: J. Biochem.
  doi: 10.1093/oxfordjournals.jbchem.a022368
– volume: 74
  start-page: 223
  year: 2004
  end-page: 234
  ident: CR18
  article-title: The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002
  publication-title: Drug Alcohol Depen.
  doi: 10.1016/j.drugalcdep.2004.02.004
– volume: 10
  start-page: 292
  year: 2009
  end-page: 305
  ident: CR40
  article-title: Determination of mineral content in methanolic safflower ( L.) seed extract and its effect on osteoblast markers
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms10010292
– volume: 95
  start-page: 351
  year: 1979
  end-page: 358
  ident: CR48
  article-title: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
  publication-title: Anal. Biochem.
  doi: 10.1016/0003-2697(79)90738-3
– volume: 58
  start-page: 381
  year: 1999
  end-page: 387
  ident: CR38
  article-title: Brain shrinkage in alcoholics: a decade on and what have we learned?
  publication-title: Prog. Neurobiol.
  doi: 10.1016/S0301-0082(98)00091-4
– volume: 63
  start-page: 1855
  year: 1994
  end-page: 1862
  ident: CR43
  article-title: Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: Effect of chronic ethanol consumption
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.1994.63051855.x
– volume: 19
  start-page: 240
  year: 2018
  end-page: 247
  ident: CR17
  article-title: Neuropsychiatric symptoms in people with Korsakoff syndrome and other alcohol-related cognitive disorders living in specialized long-term care facilities: prevalence, severity, and associated caregiver distress
  publication-title: J. Am. Med. Dir. Assoc.
  doi: 10.1016/j.jamda.2017.09.013
– volume: 16
  start-page: 71
  year: 2007
  end-page: 77
  ident: CR36
  article-title: Antioxidant properties and quantification of phenolic compounds from safflower ( L.) seeds
  publication-title: Food Sci. Biotechnol.
– volume: 32
  start-page: 210
  year: 2000
  end-page: 221
  ident: CR6
  article-title: Role of serotonin in memory impairment
  publication-title: Ann. Med.
  doi: 10.3109/07853890008998828
– volume: 133
  start-page: 115
  year: 2002
  end-page: 126
  ident: CR49
  article-title: Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain
  publication-title: Dev. Brain Res.
  doi: 10.1016/S0165-3806(02)00279-1
– volume: 203
  start-page: 296
  year: 2009
  end-page: 303
  ident: CR68
  article-title: Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats
  publication-title: Behav. Brain Res.
  doi: 10.1016/j.bbr.2009.05.016
– volume: 38
  start-page: 99
  year: 2014
  end-page: 111
  ident: CR72
  article-title: Effects of one-and three-day binge alcohol exposure in neonatal C57BL/6 mice on spatial learning and memory in adolescence and adulthood
  publication-title: Alcohol
  doi: 10.1016/j.alcohol.2013.12.001
– volume: 8
  start-page: e55839
  year: 2013
  ident: CR77
  article-title: Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke
  publication-title: Plos One
  doi: 10.1371/journal.pone.0055839
– volume: 6
  start-page: 574
  year: 1997
  end-page: 596
  ident: CR75
  article-title: A possible role for cholinergic neurons of the basal forebrain and pontomesencephalon in consciousness
  publication-title: Conscious. Cogn.
  doi: 10.1006/ccog.1997.0319
– volume: 8
  start-page: 22
  year: 1985
  end-page: 26
  ident: CR21
  article-title: Oxygen radicals in the nervous system
  publication-title: Trends Neurosci.
  doi: 10.1016/0166-2236(85)90010-4
– volume: 30
  start-page: 1500
  year: 2006
  end-page: 1505
  ident: CR80
  article-title: Enzymatic mechanisms of ethanol oxidation in the brain
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.2006.00181.x
– volume: 32
  start-page: 13787
  year: 2012
  end-page: 13795
  ident: CR12
  article-title: Acetylcholine facilitates recovery of episodic memory after brain damage
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.2947-12.2012
– volume: 21
  start-page: 84
  year: 1997
  end-page: 92
  ident: CR14
  article-title: Alcohol’s impact on kidney function
  publication-title: Alcohol Health and Res. World
– volume: 31
  start-page: 1558
  year: 2007
  end-page: 1573
  ident: CR11
  article-title: Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.2007.00450.x
– volume: 34
  start-page: 795
  year: 2014
  end-page: 805
  ident: CR25
  article-title: Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Linne)
  publication-title: Neurochem. Res.
  doi: 10.1007/s11064-008-9884-5
– volume: 49
  start-page: 415
  year: 2001
  end-page: 420
  ident: CR65
  article-title: Alcohol abuse, cognitive impairment, and mortality among older people
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1046/j.1532-5415.2001.49085.x
– volume: 22
  start-page: 304
  year: 1998
  end-page: 312
  ident: CR19
  article-title: Neuroanatomical and neurophysiological mechanisms involved in central nervous system dysfunctions induced by prenatal alcohol exposure
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.1998.tb03653.x
– volume: 45
  start-page: 287
  year: 1952
  end-page: 293
  ident: CR42
  article-title: A test of two explanations of spontaneous alternation
  publication-title: J. Comp. Physiol. Psych.
  doi: 10.1037/h0058118
– volume: 365
  start-page: 519
  year: 2005
  end-page: 530
  ident: CR55
  article-title: Alcohol and public health
  publication-title: Lancet.
  doi: 10.1016/S0140-6736(05)70276-2
– volume: 12
  start-page: 1247
  year: 2016
  end-page: 1250
  ident: CR29
  article-title: Association between alcohol and Alzheimer’s disease
  publication-title: Exp. Ther. Med.
  doi: 10.3892/etm.2016.3455
– volume: 8
  start-page: 176
  year: 2017
  end-page: 181
  ident: CR20
  article-title: Chlorogenic acid prevents alcohol-induced brain damage in neonatal rat
  publication-title: Transl. Neurosci.
  doi: 10.1515/tnsci-2017-0024
– volume: 13
  start-page: 93
  year: 1996
  end-page: 97
  ident: CR27
  article-title: Acetaldehyde-induced growth inhibition in cultured rat astroglial cells
  publication-title: Alcohol
  doi: 10.1016/0741-8329(95)02019-5
– volume: 4
  start-page: 221
  year: 1999
  end-page: 225
  ident: CR34
  article-title: Antioxidative activity of phenolic compounds in roasted safflower ( L.) seeds
  publication-title: Prev. Nutr. Food Sci.
– volume: 8
  start-page: 88
  year: 1999
  end-page: 92
  ident: CR54
  article-title: antioxidant activity of safflower ( L.) seeds
  publication-title: Food Sci. Biotechnol.
– volume: 6
  start-page: 8
  year: 2013
  end-page: 14
  ident: CR2
  article-title: Evaluation of spirulina supplementation on intermittent binge ethanol-induced neurotoxicity in dentate gyrus of rats
  publication-title: Int. J. Appl. Res. Nat. Prod.
– volume: 29
  start-page: 274
  year: 2006
  end-page: 280
  ident: CR37
  article-title: Alcohol metabolism’s damaging effects on the cell: a focus on reactive oxygen generation by the enzyme cytochromeP450 2E1
  publication-title: Alcohol Res. Health
– volume: 100
  start-page: 7919
  year: 2003
  end-page: 7924
  ident: CR24
  article-title: Selective impairment of hippocampal neurogenesis by chronic alcoholism: protective effects of an antioxidant
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.1230907100
– volume: 45
  start-page: 1542
  year: 2008
  end-page: 1550
  ident: CR22
  article-title: Mechanism of alcohol-induced oxidative stress and neuronal injury
  publication-title: Free Radic. Biol. Med.
  doi: 10.1016/j.freeradbiomed.2008.08.030
– volume: 46
  start-page: 1
  year: 2018
  end-page: 18
  ident: CR51
  article-title: Protective effect of safflower seed on cisplatin-induced renal damage in mice via oxidative stress and apoptosis-mediated pathways
  publication-title: Am. J. Chin. Med.
  doi: 10.1142/S0192415X18500015
– volume: 14
  start-page: 365
  year: 2004
  end-page: 371
  ident: CR71
  article-title: Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes
  publication-title: Brain Pathol.
  doi: 10.1111/j.1750-3639.2004.tb00079.x
– volume: 268
  start-page: 579
  year: 1990
  end-page: 583
  ident: CR60
  article-title: The role of aldehyde oxidase in ethanol-induced hepatic lipid peroxidation in the rat
  publication-title: Biochem. J.
  doi: 10.1042/bj2680579
– volume: 26
  start-page: 91
  year: 2002
  end-page: 104
  ident: CR39
  article-title: The neurobiological basis of spontaneous alternation
  publication-title: Neurosci Biobehav. Rev.
  doi: 10.1016/S0149-7634(01)00041-0
– volume: 250
  start-page: 541
  year: 1989
  end-page: 547
  ident: CR4
  article-title: Effects of ethanol on muscarinic receptor-stimulated phosphoinositide metabolism during brain development
  publication-title: J. Pharmacol. Exp. Ther.
– volume: 68
  start-page: 213
  year: 2002
  end-page: 225
  ident: CR10
  article-title: Ethanol exposure enhances cell death in the developing cerebral cortex: role of brain-derived neurotrophic factor and its signaling pathways
  publication-title: J. Neurosci. Res.
  doi: 10.1002/jnr.10208
– volume: 38
  start-page: 279
  year: 2006
  end-page: 283
  ident: CR9
  article-title: The effect of polyphenols from safflower seed on HMG-CoA reductase (HMGR) activity, LDL oxidation and Apo A1 secretion
  publication-title: Korean J. food Sci. Technol.
– volume: 186
  start-page: 421
  year: 1990
  ident: CR13
  article-title: Malondialdehyde determination as index of lipid peroxidation
  publication-title: Meth. Enzymol.
  doi: 10.1016/0076-6879(90)86135-I
– volume: 33
  start-page: 411
  year: 2000
  end-page: 420
  ident: CR58
  article-title: The effects of safflower seed powder and its fraction on bone tissue in rib-fractured rats during the recovery
  publication-title: Korean J. Nutr.
– volume: 5
  start-page: 73
  year: 2005
  end-page: 78
  ident: CR23
  article-title: Ethanol and brain damage
  publication-title: Curr. Opin. Pharmacol.
  doi: 10.1016/j.coph.2004.06.011
– start-page: 19
  year: 2010
  end-page: 27
  ident: CR16
  article-title: Why Is the Nervous System Vulnerable to Oxidative Stress?
  publication-title: Oxidative Stress and Free Radical Damage in Neurology
– volume: 29
  start-page: 221
  year: 2005
  end-page: 234
  ident: CR53
  article-title: The role of acetaldehyde in the central effects of ethanol
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1097/01.ALC.0000156185.39073.D2
– volume: 151
  start-page: 944
  year: 2014
  end-page: 950
  ident: CR73
  article-title: Antinociceptive and anti-inflammatory activities of extract and two isolated flavonoids of L
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2013.12.003
– volume: 42
  start-page: 47
  year: 2008
  end-page: 53
  ident: CR35
  article-title: Role of nitric oxide in alcohol-induced changes in lipid profile of moderate and heavy alcoholics
  publication-title: Alcohol
  doi: 10.1016/j.alcohol.2007.10.006
– volume: 244
  start-page: 147
  year: 2013
  end-page: 158
  ident: CR67
  article-title: Protective effect of curcumin against chronic alcohol-induced cognitive deficits and neuroinflammation in the adult rat brain
  publication-title: Neuroscience
  doi: 10.1016/j.neuroscience.2013.03.042
– volume: 2011
  start-page: 213
  year: 2011
  end-page: 286
  ident: CR70
  article-title: Acetaldehyde-mediated neurotoxicity: relative to fetal alcohol spectrum disorders
  publication-title: Oxid. Med. Cell Longev.
  doi: 10.1155/2011/213286
– volume: 41
  start-page: 615
  year: 1992
  end-page: 624
  ident: CR57
  article-title: Regulation and sub cellular location of nitrogen oxide synthases in RAW264.7 macrophages
  publication-title: Mol. Pharmacol.
– volume: 11
  start-page: 47
  year: 1984
  end-page: 60
  ident: CR45
  article-title: Developments of a water-maze procedure for studying a spatial learning in the rat
  publication-title: J. Neurosci. Meth.
  doi: 10.1016/0165-0270(84)90007-4
– volume: 23
  start-page: 481
  year: 2018
  ident: CR74
  article-title: Antioxidant activity and protective effects of enzyme-extracted polysaccharides on alcohol-induced liver injury
  publication-title: Molecules
  doi: 10.3390/molecules23020481
– volume: 5
  start-page: 22
  year: 1999
  end-page: 56
  ident: CR47
  article-title: Free radicals and oxidative stress in exercise-immunological aspects
  publication-title: Exerc. Immunol. Rev.
– volume: 11
  start-page: 140
  year: 2002
  end-page: 146
  ident: CR3
  article-title: Cytotoxicity of phenolic compounds isolated from seeds of safflower ( L.) on cancer cell lines
  publication-title: Food Sci. Biotechnol.
– ident: CR63
– volume: 21
  start-page: 895
  year: 2001
  end-page: 904
  ident: CR44
  article-title: Safflower seed extract lowers plasma and hepatic lipids in rats fed high-cholesterol diet
  publication-title: Nutr. Res.
  doi: 10.1016/S0271-5317(01)00293-7
– volume: 18
  start-page: 10
  year: 2008
  ident: CR52
  article-title: Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment
  publication-title: J. Neuroinflammation
  doi: 10.1186/1742-2094-5-10
– volume: 17
  start-page: 91
  year: 2016
  end-page: 101
  ident: CR7
  article-title: Anthocyanins: Are they beneficial in treating ethanol neurotoxicity?
  publication-title: Neurotox. Res.
  doi: 10.1007/s12640-009-9083-4
– volume: 833
  start-page: 202
  year: 1999
  end-page: 208
  ident: CR26
  article-title: Acetaldehyde cytotoxicity in cultured rat astrocytes
  publication-title: Brain Res.
  doi: 10.1016/S0006-8993(99)01529-2
– start-page: 173
  year: 1994
  end-page: 187
  ident: CR1
  article-title: Impairment in memory function and neurodegenerative changes in the cholinergic basal forebrain system induced by chronic intake of ethanol
  publication-title: Cell and Animal Models in Aging and Dementia Research
  doi: 10.1007/978-3-7091-9350-1_13
– volume: 232
  start-page: 723
  year: 2014
  end-page: 738
  ident: CR59
  article-title: The role of serotonin in memory: interactions with neurotransmitters and downstream signaling
  publication-title: Exp. Brain Res.
  doi: 10.1007/s00221-013-3818-4
– volume: 44
  start-page: 197
  year: 2016
  end-page: 226
  ident: CR79
  article-title: Phytochemistry and Pharmacology of L
  publication-title: Am. J. Chin. Med.
  doi: 10.1142/S0192415X16500130
– volume: 3
  start-page: 276
  year: 2009
  end-page: 283
  ident: CR15
  article-title: Salvia sahendica prevents tissue damages induced by alcohol in oxidative stress conditions: Effect on liver and kidney oxidative parameters
  publication-title: J. Med. Plants Res.
– volume: 35
  start-page: 1064
  year: 2010
  end-page: 1070
  ident: CR30
  article-title: Effects of systemic nicotine, alcohol or their combination on cholinergic markers in the frontal cortex and hippocampus of rat
  publication-title: Neurochem. Res.
  doi: 10.1007/s11064-010-0155-x
– volume: 4
  start-page: 202
  year: 2000
  end-page: 207
  ident: CR33
  article-title: Fatty acid intake and the risk of dementia and cognitive decline: a review of clinical and epidemiological studies
  publication-title: J. Nutr. Health Aging
– volume: 19
  start-page: 66
  year: 2002
  end-page: 72
  ident: CR62
  article-title: Effects of safflower seed on new bone formation
  publication-title: J. Vet. Clinic.
– volume: 77
  start-page: 591
  year: 2003
  end-page: 593
  ident: CR46
  article-title: Acetaldehyde adducts in the brain of alcoholics
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-003-0465-8
– volume: 13
  start-page: 1053
  year: 2010
  end-page: 1066
  ident: CR69
  article-title: Epigallocatechin-3-gallate ameliorates alcohol-induced cognitive dysfunctions and apoptotic neurodegeneration in the developing rat brain
  publication-title: Int. J. Neuropsychopharmacol.
  doi: 10.1017/S146114571000060X
– volume: 45
  start-page: 1910
  year: 1997
  end-page: 1914
  ident: CR78
  article-title: Antioxidative compounds isolated from safflower ( L.) oil cake
  publication-title: Chem. Pharm. Bull.
  doi: 10.1248/cpb.45.1910
– volume: 50
  start-page: 32
  year: 2004
  end-page: 37
  ident: CR8
  article-title: Effects of defatted safflower seed extract and phenolic compounds in diet on plasma and liver lipid in ovariectomized rats fed high-cholesterol diets
  publication-title: J. Nutr. Sci. Vitaminol.
  doi: 10.3177/jnsv.50.32
– volume: 133
  start-page: 524
  year: 2011
  end-page: 530
  ident: CR32
  article-title: Anti-inflammatory action of methanol extract of involves in heme oxygenase-1 induction
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2010.10.029
– volume: 2012
  start-page: 465897
  year: 2012
  ident: CR50
  article-title: Induction of oxidative stress in kidney
  publication-title: Int. J. Nephrol.
  doi: 10.1155/2012/465897
– volume: 27
  start-page: 277
  year: 2003
  end-page: 284
  ident: CR76
  article-title: Alcohol, oxidative stress, and free radical damage
  publication-title: Alcohol Res. Health
– volume: 120
  start-page: 227
  year: 1994
  end-page: 237
  ident: CR41
  article-title: Nitric oxide: a physiologic messenger
  publication-title: Ann. Intern. Med.
  doi: 10.7326/0003-4819-120-3-199402010-00009
– volume: 44
  start-page: 2951
  year: 1980
  end-page: 2954
  ident: CR56
  article-title: Conjugated serotonins and phenolic constituents in safflower seed ( L.). Argric
  publication-title: Biol. Chem.
– volume: 224
  start-page: 519
  year: 2012
  end-page: 535
  ident: CR66
  article-title: Attenuation of oxidative stress, neuroinflammation and apoptosis by prevents cognitive deficits in rats postnatally exposed ethanol
  publication-title: Psychopharmacology
  doi: 10.1007/s00213-012-2779-9
– volume: 58
  start-page: 911
  year: 2010
  end-page: 920
  ident: CR28
  article-title: Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2009.11.002
– volume: 1
  start-page: 1306
  year: 2006
  end-page: 1311
  ident: CR5
  article-title: Object recognition in rats and mice: a one-trial non-matching to-sample learning task to study ‘recognition memory’
  publication-title: Nat. Protoc.
  doi: 10.1038/nprot.2006.205
– volume: 2
  start-page: 277
  year: 1997
  end-page: 289
  ident: CR61
  article-title: Catalase and the production of brain acetaldehyde: a possible mediator for the psychopharmacological effects of ethanol
  publication-title: Addict. Biol.
  doi: 10.1080/13556219772570
– volume: 342
  start-page: 1201
  year: 1993
  end-page: 1204
  ident: CR31
  article-title: Do alcoholics drink their neurons away?
  publication-title: Lancet.
  doi: 10.1016/0140-6736(93)92185-V
– volume: 46
  start-page: 1
  year: 2018
  ident: 472_CR51
  publication-title: Am. J. Chin. Med.
  doi: 10.1142/S0192415X18500015
– volume: 74
  start-page: 223
  year: 2004
  ident: 472_CR18
  publication-title: Drug Alcohol Depen.
  doi: 10.1016/j.drugalcdep.2004.02.004
– volume: 3
  start-page: 276
  year: 2009
  ident: 472_CR15
  publication-title: J. Med. Plants Res.
– volume: 8
  start-page: 176
  year: 2017
  ident: 472_CR20
  publication-title: Transl. Neurosci.
  doi: 10.1515/tnsci-2017-0024
– volume: 6
  start-page: 574
  year: 1997
  ident: 472_CR75
  publication-title: Conscious. Cogn.
  doi: 10.1006/ccog.1997.0319
– volume: 12
  start-page: 1247
  year: 2016
  ident: 472_CR29
  publication-title: Exp. Ther. Med.
  doi: 10.3892/etm.2016.3455
– volume: 63
  start-page: 1855
  year: 1994
  ident: 472_CR43
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.1994.63051855.x
– volume: 120
  start-page: 227
  year: 1994
  ident: 472_CR41
  publication-title: Ann. Intern. Med.
  doi: 10.7326/0003-4819-120-3-199402010-00009
– volume: 232
  start-page: 723
  year: 2014
  ident: 472_CR59
  publication-title: Exp. Brain Res.
  doi: 10.1007/s00221-013-3818-4
– start-page: 19
  volume-title: Oxidative Stress and Free Radical Damage in Neurology
  year: 2010
  ident: 472_CR16
– volume: 5
  start-page: 73
  year: 2005
  ident: 472_CR23
  publication-title: Curr. Opin. Pharmacol.
  doi: 10.1016/j.coph.2004.06.011
– volume: 45
  start-page: 1542
  year: 2008
  ident: 472_CR22
  publication-title: Free Radic. Biol. Med.
  doi: 10.1016/j.freeradbiomed.2008.08.030
– volume: 23
  start-page: 481
  year: 2018
  ident: 472_CR74
  publication-title: Molecules
  doi: 10.3390/molecules23020481
– volume: 45
  start-page: 287
  year: 1952
  ident: 472_CR42
  publication-title: J. Comp. Physiol. Psych.
  doi: 10.1037/h0058118
– volume: 38
  start-page: 99
  year: 2014
  ident: 472_CR72
  publication-title: Alcohol
  doi: 10.1016/j.alcohol.2013.12.001
– volume: 77
  start-page: 591
  year: 2003
  ident: 472_CR46
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-003-0465-8
– ident: 472_CR63
– volume: 244
  start-page: 147
  year: 2013
  ident: 472_CR67
  publication-title: Neuroscience
  doi: 10.1016/j.neuroscience.2013.03.042
– volume: 17
  start-page: 91
  year: 2016
  ident: 472_CR7
  publication-title: Neurotox. Res.
  doi: 10.1007/s12640-009-9083-4
– volume: 21
  start-page: 84
  year: 1997
  ident: 472_CR14
  publication-title: Alcohol Health and Res. World
– volume: 133
  start-page: 115
  year: 2002
  ident: 472_CR49
  publication-title: Dev. Brain Res.
  doi: 10.1016/S0165-3806(02)00279-1
– volume: 2011
  start-page: 213
  year: 2011
  ident: 472_CR70
  publication-title: Oxid. Med. Cell Longev.
  doi: 10.1155/2011/213286
– volume: 11
  start-page: 140
  year: 2002
  ident: 472_CR3
  publication-title: Food Sci. Biotechnol.
– volume: 32
  start-page: 13787
  year: 2012
  ident: 472_CR12
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.2947-12.2012
– volume: 22
  start-page: 304
  year: 1998
  ident: 472_CR19
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.1998.tb03653.x
– volume: 19
  start-page: 240
  year: 2018
  ident: 472_CR17
  publication-title: J. Am. Med. Dir. Assoc.
  doi: 10.1016/j.jamda.2017.09.013
– volume: 13
  start-page: 93
  year: 1996
  ident: 472_CR27
  publication-title: Alcohol
  doi: 10.1016/0741-8329(95)02019-5
– volume: 29
  start-page: 274
  year: 2006
  ident: 472_CR37
  publication-title: Alcohol Res. Health
– volume: 16
  start-page: 71
  year: 2007
  ident: 472_CR36
  publication-title: Food Sci. Biotechnol.
– volume: 29
  start-page: 221
  year: 2005
  ident: 472_CR53
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1097/01.ALC.0000156185.39073.D2
– volume: 30
  start-page: 1500
  year: 2006
  ident: 472_CR80
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.2006.00181.x
– volume: 13
  start-page: 1053
  year: 2010
  ident: 472_CR69
  publication-title: Int. J. Neuropsychopharmacol.
  doi: 10.1017/S146114571000060X
– volume: 41
  start-page: 615
  year: 1992
  ident: 472_CR57
  publication-title: Mol. Pharmacol.
  doi: 10.1016/S0026-895X(25)08977-1
– volume: 5
  start-page: 22
  year: 1999
  ident: 472_CR47
  publication-title: Exerc. Immunol. Rev.
– volume: 49
  start-page: 415
  year: 2001
  ident: 472_CR65
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1046/j.1532-5415.2001.49085.x
– volume: 342
  start-page: 1201
  year: 1993
  ident: 472_CR31
  publication-title: Lancet.
  doi: 10.1016/0140-6736(93)92185-V
– volume: 4
  start-page: 221
  year: 1999
  ident: 472_CR34
  publication-title: Prev. Nutr. Food Sci.
– volume: 11
  start-page: 47
  year: 1984
  ident: 472_CR45
  publication-title: J. Neurosci. Meth.
  doi: 10.1016/0165-0270(84)90007-4
– volume: 35
  start-page: 1064
  year: 2010
  ident: 472_CR30
  publication-title: Neurochem. Res.
  doi: 10.1007/s11064-010-0155-x
– volume: 68
  start-page: 213
  year: 2002
  ident: 472_CR10
  publication-title: J. Neurosci. Res.
  doi: 10.1002/jnr.10208
– volume: 95
  start-page: 351
  year: 1979
  ident: 472_CR48
  publication-title: Anal. Biochem.
  doi: 10.1016/0003-2697(79)90738-3
– volume: 50
  start-page: 32
  year: 2004
  ident: 472_CR8
  publication-title: J. Nutr. Sci. Vitaminol.
  doi: 10.3177/jnsv.50.32
– volume: 58
  start-page: 911
  year: 2010
  ident: 472_CR28
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2009.11.002
– volume: 33
  start-page: 411
  year: 2000
  ident: 472_CR58
  publication-title: Korean J. Nutr.
– volume: 27
  start-page: 277
  year: 2003
  ident: 472_CR76
  publication-title: Alcohol Res. Health
– volume: 833
  start-page: 202
  year: 1999
  ident: 472_CR26
  publication-title: Brain Res.
  doi: 10.1016/S0006-8993(99)01529-2
– volume: 38
  start-page: 279
  year: 2006
  ident: 472_CR9
  publication-title: Korean J. food Sci. Technol.
– volume: 8
  start-page: 22
  year: 1985
  ident: 472_CR21
  publication-title: Trends Neurosci.
  doi: 10.1016/0166-2236(85)90010-4
– volume: 32
  start-page: 210
  year: 2000
  ident: 472_CR6
  publication-title: Ann. Med.
  doi: 10.3109/07853890008998828
– volume: 31
  start-page: 1558
  year: 2007
  ident: 472_CR11
  publication-title: Alcohol Clin. Exp. Res.
  doi: 10.1111/j.1530-0277.2007.00450.x
– volume: 10
  start-page: 292
  year: 2009
  ident: 472_CR40
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms10010292
– volume: 44
  start-page: 2951
  year: 1980
  ident: 472_CR56
  publication-title: Biol. Chem.
– volume: 6
  start-page: 8
  year: 2013
  ident: 472_CR2
  publication-title: Int. J. Appl. Res. Nat. Prod.
– volume: 1
  start-page: 1306
  year: 2006
  ident: 472_CR5
  publication-title: Nat. Protoc.
  doi: 10.1038/nprot.2006.205
– volume: 250
  start-page: 541
  year: 1989
  ident: 472_CR4
  publication-title: J. Pharmacol. Exp. Ther.
  doi: 10.1016/S0022-3565(25)22244-3
– volume: 44
  start-page: 197
  year: 2016
  ident: 472_CR79
  publication-title: Am. J. Chin. Med.
  doi: 10.1142/S0192415X16500130
– volume: 125
  start-page: 910
  year: 1999
  ident: 472_CR64
  publication-title: J. Biochem.
  doi: 10.1093/oxfordjournals.jbchem.a022368
– volume: 268
  start-page: 579
  year: 1990
  ident: 472_CR60
  publication-title: Biochem. J.
  doi: 10.1042/bj2680579
– volume: 45
  start-page: 1910
  year: 1997
  ident: 472_CR78
  publication-title: Chem. Pharm. Bull.
  doi: 10.1248/cpb.45.1910
– volume: 58
  start-page: 381
  year: 1999
  ident: 472_CR38
  publication-title: Prog. Neurobiol.
  doi: 10.1016/S0301-0082(98)00091-4
– volume: 2012
  start-page: 465897
  year: 2012
  ident: 472_CR50
  publication-title: Int. J. Nephrol.
  doi: 10.1155/2012/465897
– volume: 19
  start-page: 66
  year: 2002
  ident: 472_CR62
  publication-title: J. Vet. Clinic.
– volume: 224
  start-page: 519
  year: 2012
  ident: 472_CR66
  publication-title: Psychopharmacology
  doi: 10.1007/s00213-012-2779-9
– volume: 34
  start-page: 795
  year: 2014
  ident: 472_CR25
  publication-title: Neurochem. Res.
  doi: 10.1007/s11064-008-9884-5
– volume: 14
  start-page: 365
  year: 2004
  ident: 472_CR71
  publication-title: Brain Pathol.
  doi: 10.1111/j.1750-3639.2004.tb00079.x
– volume: 186
  start-page: 421
  year: 1990
  ident: 472_CR13
  publication-title: Meth. Enzymol.
  doi: 10.1016/0076-6879(90)86135-I
– volume: 4
  start-page: 202
  year: 2000
  ident: 472_CR33
  publication-title: J. Nutr. Health Aging
– volume: 203
  start-page: 296
  year: 2009
  ident: 472_CR68
  publication-title: Behav. Brain Res.
  doi: 10.1016/j.bbr.2009.05.016
– volume: 8
  start-page: e55839
  year: 2013
  ident: 472_CR77
  publication-title: Plos One
  doi: 10.1371/journal.pone.0055839
– volume: 42
  start-page: 47
  year: 2008
  ident: 472_CR35
  publication-title: Alcohol
  doi: 10.1016/j.alcohol.2007.10.006
– volume: 133
  start-page: 524
  year: 2011
  ident: 472_CR32
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2010.10.029
– volume: 2
  start-page: 277
  year: 1997
  ident: 472_CR61
  publication-title: Addict. Biol.
  doi: 10.1080/13556219772570
– volume: 151
  start-page: 944
  year: 2014
  ident: 472_CR73
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2013.12.003
– start-page: 173
  volume-title: Cell and Animal Models in Aging and Dementia Research
  year: 1994
  ident: 472_CR1
  doi: 10.1007/978-3-7091-9350-1_13
– volume: 8
  start-page: 88
  year: 1999
  ident: 472_CR54
  publication-title: Food Sci. Biotechnol.
– volume: 21
  start-page: 895
  year: 2001
  ident: 472_CR44
  publication-title: Nutr. Res.
  doi: 10.1016/S0271-5317(01)00293-7
– volume: 365
  start-page: 519
  year: 2005
  ident: 472_CR55
  publication-title: Lancet.
  doi: 10.1016/S0140-6736(05)70276-2
– volume: 18
  start-page: 10
  year: 2008
  ident: 472_CR52
  publication-title: J. Neuroinflammation
  doi: 10.1186/1742-2094-5-10
– volume: 26
  start-page: 91
  year: 2002
  ident: 472_CR39
  publication-title: Neurosci Biobehav. Rev.
  doi: 10.1016/S0149-7634(01)00041-0
– volume: 100
  start-page: 7919
  year: 2003
  ident: 472_CR24
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.1230907100
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Snippet Chronic alcohol consumption induces damage to the brain that can cause various forms of dementia. An abundance of acetaldehyde is produced by excessive alcohol...
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pubmed
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StartPage 1475
SubjectTerms Acetaldehyde
Acetylcholinesterase
alcohol abuse
alcohol drinking
Alcohol use
Alcoholic beverages
Alcohols
Apoptosis
brain
Brain damage
Brain injury
Carthamus tinctorius
Chemistry
Chemistry and Materials Science
cognition
Cognitive ability
cognitive disorders
Dementia
Dementia disorders
enzyme activity
Food Science
inflammation
Kidneys
Lipid peroxidation
Lipids
Liver
memory
Mice
neurons
Nitric oxide
Nutrition
Object recognition
Oral administration
Oxidative stress
Pattern recognition
Peroxidation
protective effect
식품과학
Title Protective effect of Carthamus tinctorius L. seed on oxidative stress and cognitive impairment induced by chronic alcohol consumption in mice
URI https://link.springer.com/article/10.1007/s10068-018-0472-4
https://www.ncbi.nlm.nih.gov/pubmed/30319858
https://www.proquest.com/docview/2116083700
https://www.proquest.com/docview/2120200946
https://www.proquest.com/docview/2220847029
https://pubmed.ncbi.nlm.nih.gov/PMC6170295
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002394277
Volume 27
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