Chemiluminescence Platforms in Immunoassay and DNA Analyses

Chemiluminescent (CL) detection techniques for DNA assays and immunoassays have become very popular in recent years. This review discusses recent advances in those CL assays that have occurred over the last few years. In the monoplex assay section, different classes of CL labels including nanopartic...

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Bibliographic Details
Published inAnalytical Sciences Vol. 25; no. 5; pp. 587 - 597
Main Authors FAN, Aiping, CAO, Zhijuan, LI, Huan, KAI, Masaaki, LU, Jianzhong
Format Journal Article
LanguageEnglish
Published Singapore The Japan Society for Analytical Chemistry 01.05.2009
Springer Nature Singapore
Japan Science and Technology Agency
Subjects
Analytical Chemistry
Animals
Chemistry
DNA - analysis
Electrochemistry
Humans
Immunoassay - methods
Luminescent Measurements - methods
Reviews
Staining and Labeling
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Summary:Chemiluminescent (CL) detection techniques for DNA assays and immunoassays have become very popular in recent years. This review discusses recent advances in those CL assays that have occurred over the last few years. In the monoplex assay section, different classes of CL labels including nanoparticle, DNAzyme, acridinium ester, enzyme and luminol-based CL assays are reviewed concerning the detection of DNAs and proteins. In the multiplex assay section, both spatial resolution and substrate zone-resolved techniques are discussed.
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ISSN:0910-6340
1348-2246
DOI:10.2116/analsci.25.587