The effects of milk as a food matrix for polyphenols on the excretion profile of cocoa ( − )-epicatechin metabolites in healthy human subjects

• Published in: British journal of nutrition Vol. 100; no. 4; pp. 846 - 851
• Main Authors: Roura, Elena, Andrés-Lacueva, Cristina, Estruch, Ramon, Lourdes Mata Bilbao, M., Izquierdo-Pulido, Maria, Lamuela-Raventós, Rosa M.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.10.2008
• Subjects: ( − )-Epicatechin metabolites; Adolescent; Adult; analogs & derivatives; Animals; Biological and medical sciences; Cacao; Catechin; Catechin - analogs & derivatives; Catechin - metabolism; Catechin - urine; Clinical trials; Cocoa; Cocoa powder; Cross-Over Studies; Diet; epicatechin; Excretion; Feeding. Feeding behavior; Female; Flavonoids; Flavonoids - metabolism; Flavonoids - urine; Food; Food matrix; Fundamental and applied biological sciences. Psychology; Glucuronide; Glucuronides; Glucuronides - urine; health status; Humans; Ingestion; Linear Models; Liquid chromatography; Male; men; Metabolism; Metabolites; Middle Aged; Milk; Molecular weight; Nutrition; pharmacokinetics; Phenols; Phenols - metabolism; Phenols - urine; Polyphenols; Smoking; Sulfate excretion; Sulfates; Sulfuric Acid Esters; Sulfuric Acid Esters - urine; test meals; Urine; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Water purification; women; Young Adult; Urine; Sulfate excretion; Flavonoids; Cocoa powder; Glucuronide; ( − )-Epicatechin metabolites; Human; Excretion; Healthy subject; Metabolite; Sulfates; Cocoa; Flavonoid; Powder; Vertebrata; Polyphenol; Mammalia; (-)-Epicatechin metabolites: Cocoa powder: Flavonoids: Urine: Glucuronide: Sulfate excretion; Food; Milk

The effect of different food matrices on the metabolism and excretion of polyphenols is uncertain. The objective of the study was to evaluate the possible effect of milk on the excretion of ( − )-epicatechin metabolites from cocoa powder after its ingestion with and without milk. Twenty-one voluntee...