Natural History of Invasive Papillary Breast Carcinoma Followed for 10 Years: A Case Report and Literature Review

• Published in: Case reports in medicine Vol. 2017; no. 2017; pp. 1 - 4
• Main Authors: Suh, Yong Joon, Kwon, Tae Jung, Shin, Hyukjai
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2017; Hindawi; John Wiley & Sons, Inc; Hindawi Limited; Wiley
• Subjects: Breast cancer; Care and treatment; Case Report; Case studies; Development and progression; Diagnosis; Metastasis; South Korea
• ISSN: 1687-9627; 1687-9635
• DOI: 10.1155/2017/3725391

Diachronic research on untreated breast cancer completely depends on past medical records when no more recent, advanced methods are available. Herein, we report a case of invasive papillary breast carcinoma followed for 10 years in a 59-year-old woman who refused any treatment. The diagnosis was based on core needle biopsies. At the patient’s first visit in July 2006, the tumor measured 10.4 × 7.2 × 3.5 cm. It was staged as IIIB (T4bN1). In May 2016, the tumor was staged as IIIC (T4bN3a). In the past 10 years, the tumor has increased to 12.1 × 9.0 × 4.2 cm. However, a whole-body bone scan and 18F-FDG PET/CT showed no evidence of distant metastasis. Immunohistochemistry results, corresponding to biopsies taken at subsequent examinations, have remained unaltered since 2006. The tumor was estrogen/progesterone receptor-positive and C-erbB2 expression was not detected. The Ki-67 labeling index was around 10%.