Cumulative dietary risk characterisation of pesticides that have chronic effects on the thyroid

• Published in: EFSA journal Vol. 18; no. 4; pp. e06088 - n/a
• Main Authors: Craig, Peter S, Dujardin, Bruno, Hart, Andy, Hernandez‐Jerez, Antonio F, Hougaard Bennekou, Susanne, Kneuer, Carsten, Ossendorp, Bernadette, Pedersen, Ragnor, Wolterink, Gerrit, Mohimont, Luc
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.04.2020; John Wiley and Sons Inc; Wiley
• Subjects: Chronic effects; cumulative risk assessment; Diet; Estimates; expert knowledge elicitation; Exposure; Hyperplasia; Hypertrophy; Hypothyroidism; Metabolites; Monitoring; Pesticide residues; Pesticides; Populations; probabilistic modelling; Public health; Regulation; Risk assessment; Risk management; Scientific Report; Software; Software development tools; Thyroid; Thyroid gland; Toddlers; Uncertainty analysis; probabilistic modelling; pesticide residues; thyroid; expert knowledge elicitation; cumulative risk assessment

A retrospective chronic cumulative risk assessment of dietary exposure to pesticide residues, supported by an uncertainty analysis based on expert knowledge elicitation, was conducted for two effects on the thyroid, hypothyroidism and parafollicular cell (C‐cell) hypertrophy, hyperplasia and neoplas...