COVID-19 and helminth infection: Beyond the Th1/Th2 paradigm

[...]in these South American populations, the high prevalence of intestinal parasitosis with soil-transmitted helminths does not appear to have provided a benefit in terms of SARS-CoV-2-related morbidity or mortality. [...]a recent study by Yatsunenko and colleagues [12] has revealed differences in...

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Published inPLoS neglected tropical diseases Vol. 15; no. 5; p. e0009402
Main Authors Paniz-Mondolfi, Alberto E., Ramírez, Juan David, Delgado-Noguera, Lourdes A., Rodriguez-Morales, Alfonso J., Sordillo, Emilia M.
Format Journal Article
LanguageEnglish
Published San Francisco Public Library of Science 01.05.2021
Public Library of Science (PLoS)
Subjects
Biology and Life Sciences
Care and treatment
Clinical outcomes
Coronaviruses
COVID-19
Cytokines
Development and progression
Disease transmission
Genetic aspects
Health aspects
Helminthiasis
Immune response
Infections
Interleukins
Intestine
Lymphocytes T
Medicine
Medicine and Health Sciences
Metabolism
Morbidity
Mortality
Pandemics
Parasites
Parasitic diseases
Pathology
People and places
Severe acute respiratory syndrome coronavirus 2
Surveillance
Tropical diseases
Viewpoints
United States
Brazil
New York
Venezuela
Colombia
United States > US
Africa
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Summary:[...]in these South American populations, the high prevalence of intestinal parasitosis with soil-transmitted helminths does not appear to have provided a benefit in terms of SARS-CoV-2-related morbidity or mortality. [...]a recent study by Yatsunenko and colleagues [12] has revealed differences in bacterial assemblages and functional gene repertoires between Amerindians in the Venezuelan Amazon when compared to US residents. [...]it is essential to remember the manifold negative effects of intestinal parasitosis.
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The authors have declared that no competing interests exist.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0009402