Casein Kinase II in Theileriosis

• Published in: Science (American Association for the Advancement of Science) Vol. 267; no. 5199; pp. 834 - 836
• Main Author: ole-MoiYoi, Onesmo K.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for the Advancement of Science 10.02.1995; American Association for the Advancement of Science; The American Association for the Advancement of Science
• Subjects: Animal Husbandry; Animals; B lymphocytes; Biological and medical sciences; Carcinogenesis; Casein Kinase II; Cattle; Cell cycle; Cell Division; Cell growth; Cell Transformation, Neoplastic; Daughter cells; Disease; Diseases; Experimental protozoal diseases and models; Immunoproliferative disorders; Infectious diseases; Livestock; Lymphocyte Activation; Lymphocytes; Lymphoma - etiology; Lymphoproliferative disorders; Medical sciences; Mice; Mice, Transgenic; Parasite hosts; Parasites; Parasitic diseases; Perspectives; Protein-Serine-Threonine Kinases - metabolism; Proteins; Protozoal diseases; Signal Transduction; Sporozoites; T lymphocytes; T-Lymphocytes - enzymology; T-Lymphocytes - parasitology; T-Lymphocytes - physiology; Theileria parva - enzymology; Theileria parva - physiology; Theileriasis - enzymology; Theileriasis - parasitology; Transgenic animals; Kenya; Africa; Theileriosis; Protozoa; Protozoal disease; Bovine; Enzyme; Theileria parva; Transferases; Parasitosis; Infection; Vertebrata; Mammalia; Enzymatic activity; Protein kinase; Artiodactyla; Sporozoa; Ungulata
• ISSN: 0036-8075; 1095-9203
• DOI: 10.1126/science.7846527

East Coast fever, caused by the parasite Theileria parva, is an acute, leukemia-like disease that strikes many livestock in Africa. Researchers have discovered evidence for the contributing role of casein kinase II alpha in oncogenic transformation of the disease.