Modulating Mutation Rates in the Wild

What happens to wild isolates of Escherichia coli bacteria from all walks of life when you put them in a laboratory and starve them? In their Perspective, Rosenberg and Hastings discuss just such a scenario and explain the increased rate of stress-induced mutagenesis--a strategy that may hasten evol...

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 300; no. 5624; pp. 1382 - 1383
Main Authors Rosenberg, Susan M., Hastings, P. J.
Format Journal Article
LanguageEnglish
Published Washington American Association for the Advancement of Science 30.05.2003
The American Association for the Advancement of Science
Subjects
Bacteria
Biodiversity
Case Studies
Causes of
Correlation
DNA
DNA damage
DNA mismatch repair
E coli
Environmental aspects
Evolution
Genetic mutation
Genetics
Laboratories
Microbiology
Mutagenesis
Mutation
Mutation (Biology)
Oxidative stress
Perspectives
Starvation
Steepest descent method
United States
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ISSN0036-8075
1095-9203
DOI10.1126/science.1085691

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Summary:What happens to wild isolates of Escherichia coli bacteria from all walks of life when you put them in a laboratory and starve them? In their Perspective, Rosenberg and Hastings discuss just such a scenario and explain the increased rate of stress-induced mutagenesis--a strategy that may hasten evolution--in starved, aging bacterial colonies derived from wild isolates
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.1085691