Does comorbid Social Anxiety Disorder impact the clinical presentation of principal Major Depressive Disorder?

• Published in: Journal of affective disorders Vol. 100; no. 1; pp. 241 - 247
• Main Authors: Dalrymple, Kristy L, Zimmerman, Mark
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.06.2007; Elsevier
• Subjects: Adolescent; Adult; Adult and adolescent clinical studies; Aged; Aged, 80 and over; Anxiety disorders. Neuroses; Biological and medical sciences; Comorbidity; Depression; Depressive Disorder, Major - diagnosis; Depressive Disorder, Major - epidemiology; Depressive Disorder, Major - psychology; Female; Humans; Major Depressive Disorder; Male; Medical sciences; Middle Aged; Mood disorders; Phobia; Phobic Disorders - diagnosis; Phobic Disorders - epidemiology; Phobic Disorders - psychology; Prevalence; Psychiatry; Psychology; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychosocial functioning; Severity; Severity of Illness Index; Social Anxiety Disorder; Severity; Social Anxiety Disorder; Psychosocial functioning; Comorbidity; Major Depressive Disorder; Mood disorder; Social phobia; Anxiety disorder; Clinical form; Depression; Concomitant disease; Social behavior; Social interaction; Seventy
• ISSN: 0165-0327; 1573-2517
• DOI: 10.1016/j.jad.2006.10.014

Abstract Background Although previous research has examined comorbidity in principal Social Anxiety Disorder (SAD), few studies have examined the disorders for which those with comorbid SAD seek treatment. Further, studies have shown that depressive disorders often are associated with SAD, but few have examined the clinical characteristics of patients with this particular comorbidity. Method The current study examined the prevalence of various principal Axis I disorders in 577 individuals diagnosed with comorbid SAD. Results Consistent with previous research, Major Depressive Disorder (MDD) was the most frequent principal diagnosis in patients with comorbid SAD. Those with principal MDD and comorbid SAD (MDD-SAD) were compared to those with MDD without SAD (MDD) on demographic and clinical characteristics. Patients with MDD-SAD versus those with MDD were more severe in terms of social functioning, duration of depressive episode, suicidal ideation, time out of work, presence of current alcohol abuse/dependence, and age of onset of MDD. Social functioning, duration of episode, suicidal ideation, and age of onset of MDD remained significant even after controlling for additional comorbid disorders. Conclusions Findings suggest the need for future research to determine how treatments could be adapted for this commonly occurring comorbidity.