The origin and function of tumor-associated macrophages

• Published in: Cellular & molecular immunology Vol. 12; no. 1; pp. 1 - 4
• Main Authors: Liu, Yang, Cao, Xuetao
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.01.2015; Nature Publishing Group
• Subjects: Animals; Antibodies; Biomedical and Life Sciences; Biomedicine; Female; Immunology; Macrophages; Macrophages - immunology; Mammary Neoplasms, Animal - immunology; Mammary Neoplasms, Animal - pathology; Medical Microbiology; Microbiology; Research Highlight; Tumors; Vaccine; 免疫反应; 免疫应答; 免疫抑制; 免疫治疗; 巨噬细胞; 抑制剂; 肿瘤免疫; 起源
• ISSN: 1672-7681; 2042-0226; 2042-0226
• DOI: 10.1038/cmi.2014.83

Identifying the cellular and molecular suppressors of the immune response against tumors is a popular topic in the field of tumor immunology that will provide new targets for the cancer immunotherapy. Suppressing the suppressor is a very attractive approach to enhan- cing the anti-tumor immune response by reversing the immunosuppression or blocking immune escape in the late stages of cancer progression.