Age‐related differences in self‐report and objective measures of cognitive function in older patients prior to chemotherapy

• Published in: Nursing open Vol. 9; no. 2; pp. 1040 - 1051
• Main Authors: Utne, Inger, Løyland, Borghild, Grov, Ellen Karine, Rasmussen, Hege Lund, Torstveit, Ann Helen, Paul, Steven M., Ritchie, Christine, Lindemann, Kristina, Vistad, Ingvild, Rodríguez‐Aranda, Claudia, Miaskowski, Christine
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2022; Wiley; John Wiley and Sons Inc
• Subjects: Age; Aged; Aging; Breast cancer; cancer; Cancer therapies; Chemotherapy; Cognition; Cognitive ability; cognitive function; Colorectal cancer; Comorbidity; Cross-Sectional Studies; Executive function; Gynecology; Humans; Memory; Neuropsychology; older adult; Older people; Oncology; Patients; patient‐reported outcomes; performance‐based outcomes; Quality of Life; Questionnaires; Self Report; Tinnitus; Trail Making Test; cognitive function; older adult; patient-reported outcomes; cancer; performance-based outcomes
• ISSN: 2054-1058; 2054-1058
• DOI: 10.1002/nop2.1141

Aim Evaluate for differences in demographic and clinical characteristics and subjective and objective measures of cognitive function (CF) between younger older adults (YOA, 60–69 years) and older adults (OA, ≥70 years). Design Cross‐sectional. Methods Older oncology patients (n = 139) completed subjective (Attentional Function Index, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC) CF scale) and objective (Montreal Cognitive Assessment, Trail Making Test (TMT) A & B) measures of CF prior to chemotherapy. Data were analyzed using parametric and nonparametric tests. Results No differences were found between the two groups for any of the subjective or objective CF measures, except that OA patients had higher TMT B scores. Compared with the general population, OAs had significantly higher EORTC CF scores and YOAs had significantly worse scores for all of the objective tests. Clinically meaningful difference between group differences was found for the TMT B test.