Effectiveness of Automated Treatment Planning for Left-sided Breast in Flattening Filter-free Photon Beams

Purpose: Electronic compensator is a time-consuming technique for breast cancer radiation treatment planning, consequently, this presents challenges for the development of automated treatment planning for the treatment plan. Thus, this study aimed to investigate the use of automated treatment planni...

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Published inJournal of medical physics Vol. 49; no. 4; pp. 701 - 705
Main Authors Tansangworn, Prasit, Chatchumnan, Nichakan, Saksornchai, Kitwadee, Kingkaew, Sakda, Vimolnoch, Mananchaya, Oonsiri, Puntiwa, Oonsiri, Sornjarod
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer - Medknow 01.10.2024
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Edition2
Subjects
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ISSN0971-6203
1998-3913
DOI10.4103/jmp.jmp_95_24

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Summary:Purpose: Electronic compensator is a time-consuming technique for breast cancer radiation treatment planning, consequently, this presents challenges for the development of automated treatment planning for the treatment plan. Thus, this study aimed to investigate the use of automated treatment planning software for the left breast. Subjects and Methods: Thirty-eight patients with left-sided breast cancer without locoregional nodes were treated with a prescribed dose of 42.4 Gy in 16 fractions. Treatment planning was performed using electronic compensators. In addition, automated treatment planning techniques were utilized, which involved automated plan generation. This facilitated the comparison of dosimetric parameters: target volume (Dmax, homogeneity index [HI], and conformity index [CI]), organs at risk, plan parameters, and quality assurance. Results: The automated treatment planning exerted lower Dmax of PTV_Eval compared to electronic compensator techniques, that is, 43.4 ± 1.1 Gy and 43.9 ± 1.1 Gy, respectively (P < 0.05). Similarly, the HI of automated treatment planning was lower than other techniques, 0.10 ± 0.04 and 0.08 ± 0.03, respectively (P < 0.05). However, there were no significant differences in the CI or organs at risk between the two techniques (P = 0.11). In plan parameters, automated treatment planning required lower monitor units compared to the electronic compensator techniques, i.e., 534.3 ± 47.4 and 724.5 ± 117.9, respectively (P < 0.05). Furthermore, the automated treatment planning significantly reduced treatment time compared to electronic compensator techniques, that is, 2.3 ± 0.5 and 41.8 ± 15.1 min, respectively (P < 0.05). Conclusions: Automated treatment planning improved the treatment plan homogeneity, reduced hotspots, enhanced treatment planning efficiency, and reduced treatment planning time and doses comparable to those of normal organs.
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ISSN:0971-6203
1998-3913
DOI:10.4103/jmp.jmp_95_24