Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction

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Published inMolecular and Cellular Biology Vol. 21; no. 21; pp. 7429 - 7441
Main Authors Elowe, Sabine, Holland, Sacha J., Kulkarni, Sarang, Pawson, Tony
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.11.2001
Taylor & Francis
Subjects
Animals
Blotting, Western
Cell Division
Cell Growth and Development
Cell Line
COS Cells
Cytoplasm - metabolism
Cytoskeleton - metabolism
DNA, Complementary - metabolism
Down-Regulation
Enzyme Activation
EphB2 protein
Ephrin-B1
Fibronectins - metabolism
GTP
GTPase-activating protein
Humans
MAP Kinase Signaling System
Membrane Proteins - metabolism
Mitogen-Activated Protein Kinase 1 - metabolism
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases - metabolism
Neurites - metabolism
Neurons - metabolism
p120 protein
Precipitin Tests
Protein Binding
Protein Structure, Tertiary
ras Proteins - metabolism
Rats
Receptor Protein-Tyrosine Kinases - chemistry
Receptor Protein-Tyrosine Kinases - metabolism
Receptor, EphB2
Receptor, EphB4
Receptors, Eph Family
Signal Transduction
Time Factors
Tumor Cells, Cultured
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Summary:Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to MCB .asm.org, visit: MCB       
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Present address: Rigel Inc., South San Francisco, CA 94080.
Corresponding author. Mailing address: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Ave., Toronto, Ontario, Canada M5G 1X5. Phone: (416) 586-8262. Fax: (416) 586-8869. E-mail: pawson@mshri.on.ca.
ISSN:0270-7306
1098-5549
1098-5549
DOI:10.1128/MCB.21.21.7429-7441.2001