Multiple hamartoma syndrome: clinicoradiological evaluation and histopathological correlation with brief review of literature

• Published in: Indian journal of dermatology Vol. 59; no. 6; pp. 598 - 601
• Main Authors: Monga, Emma, Gupta, Prashant K, Munshi, Avinash, Agarwal, Sudhi
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.11.2014; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Breasts; Care and treatment; Case Report; Case studies; Cowden syndrome; Diagnosis; Hematology; Medical imaging; Medical treatment; mucocutaneous papilloma; Multiple hamartoma syndrome; NMR; Nuclear magnetic resonance; phosphatase and tensin homolog; Tomography; Cowden syndrome; mucocutaneous papilloma; phosphatase and tensin homolog; multiple hamartoma syndrome
• ISSN: 0019-5154; 1998-3611
• DOI: 10.4103/0019-5154.143535

Cowden syndrome (CS) or multiple hamartoma syndromes (MHSs) is an uncommon condition and characterized by mucocutaneous lesions which may be associated with the lesions of breast, thyroid, gastrointestinal tract, skin, and often of central nervous system. A thorough evaluation of Cowden's disease is essential due to increased risk of malignancy in an organ or system of the affected patients. We are reporting a case of female patient who presented with multiple mucocutaneous papilloma associated with involvement of multiple organs and systems. The diagnosis was confirmed by multimodality diagnostic approach. This rare entity has not being reviewed in Indian literature till date. Being a rare case, we are discussing MHS with its clinicoradiological and histopathological correlation along with brief review of literature.