Atypical presentation of extraspinal neurofibroma presenting with acute-onset monoparesis and Horner's syndrome: Case report and review of literature

• Published in: Journal of craniovertebral junction and spine Vol. 10; no. 3; pp. 188 - 191
• Main Authors: Nehete, Lokesh, Konar, Subhas, Nandeesh, B, Shukla, Dhaval, Devi, B
• Format: Journal Article
• Language: English
• Published: Mumbai Wolters Kluwer India Pvt. Ltd 01.07.2019; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Bone surgery; Case Report; Case reports; extraspinal; Fibroblasts; Genetic disorders; Growth factors; Hemorrhage; horner's syndrome; Neck pain; neurofibromatosis; Neurological disorders; NMR; Nuclear magnetic resonance; outcome; Trauma; Tumor removal; Tumors; Veins & arteries; Horner's syndrome; neurofibromatosis; Extraspinal; outcome
• ISSN: 0974-8237; 0976-9285
• DOI: 10.4103/jcvjs.JCVJS_86_18

The clinical presentation of spinal or extraspinal neurofibroma is radiculopathy or myelopathy, pain, and motor weakness. Extraspinal neurofibroma presenting with acute-onset monoparesis and Horner's syndrome is very rare. We report the case of a 55-year-old female who presented with acute-onset monoparesis of the left upper limb along with left-side drooping of the eyelid. Imaging revealed C6-D2 extraspinal solitary mass lesion lateral to spinous process with bleed without intraspinal component. The patient underwent an anterior cervical approach and excision of the tumor. Final biopsy report was a neurofibroma. At 3-year follow-up, she recovered from motor weakness, and Horner's syndrome subsided. Extraspinal neurofibroma can present with acute bleed, and surgical outcome is superior in early intervention.