Diurnal variations of brown fat thermogenesis and fat oxidation in humans

• Published in: International Journal of Obesity Vol. 45; no. 11; pp. 2499 - 2505
• Main Authors: Matsushita, Mami, Nirengi, Shinsuke, Hibi, Masanobu, Wakabayashi, Hitoshi, Lee, Sang-Il, Domichi, Masayuki, Sakane, Naoki, Saito, Masayuki
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.11.2021; Nature Publishing Group UK
• Subjects: Adipose tissue; Adipose tissue (brown); Adipose Tissue, Brown - metabolism; Adipose Tissue, Brown - physiology; Adult; Body fat; Brown adipose tissue; Circadian Rhythm - physiology; Circadian rhythms; Diurnal variations; Emission analysis; Energy expenditure; Energy metabolism; Fat metabolism; Female; Glucose; Health aspects; Humans; Male; Medical research; Medicine, Experimental; Metabolic disorders; Morning; Obesity; Oxidation; Physiological aspects; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Positron-Emission Tomography - statistics & numerical data; Skin temperature; Substrates; Thermogenesis; Thermogenesis - physiology; Time Factors; Japan

Disturbed circadian rhythm is associated with an increased risk of obesity and metabolic disorders. Brown adipose tissue (BAT) is a site of nonshivering thermogenesis (NST) and plays a role in regulating whole-body energy expenditure (EE), substrate metabolism, and body fatness. In this study, we ex...