Generation of Reactive Oxygen Species (ROS) by Harmful Algal Bloom (HAB)-Forming Phytoplankton and Their Potential Impact on Surrounding Living Organisms

• Published in: Antioxidants Vol. 11; no. 2; p. 206
• Main Authors: Cho, Kichul, Ueno, Mikinori, Liang, Yan, Kim, Daekyung, Oda, Tatsuya
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 22.01.2022; MDPI
• Subjects: Algae; Aquaculture; Aquatic environment; Aquatic microorganisms; Cell surface; Chattonella; Climate change; Fish; Fisheries; harmful algae bloom (HAB) species; Hydrogen peroxide; Hydroxyl radicals; marine microalgae; Microorganisms; Mortality; NAD(P)H oxidase; nitric oxide (NO); Physiology; Phytoplankton; Poisoning; Reactive oxygen species; reactive oxygen species (ROS); Review; Shellfish; Tuna; Water quality; Japan; marine microalgae; nitric oxide (NO); reactive oxygen species (ROS); harmful algae bloom (HAB) species; Chattonella
• ISSN: 2076-3921; 2076-3921
• DOI: 10.3390/antiox11020206

Most marine phytoplankton with relatively high ROS generation rates are categorized as harmful algal bloom (HAB)-forming species, among which genera is the highest ROS-producing phytoplankton. In this review, we examined marine microalgae with ROS-producing activities, with focus on genera. Several studies suggest that produces superoxide via the activities of an enzyme similar to NADPH oxidase located on glycocalyx, a cell surface structure, while hydrogen peroxide is generated inside the cell by different pathways. Additionally, hydroxyl radical has been detected in cell suspension. By the physical stimulation, such as passing through between the gill lamellas of fish, the glycocalyx is easily discharged from the flagellate cells and attached on the gill surface, where ROS are continuously produced, which might cause gill tissue damage and fish death. Comparative studies using several strains of showed that ROS production rate and ichthyotoxicity of is well correlated. Furthermore, significant levels of ROS have been reported in other raphidophytes and dinoflagellates, such as and . is the most extensively studied phytoplankton in terms of ROS production and its biological functions. Therefore, this review examined the potential ecophysiological roles of extracellular ROS production by marine microalgae in aquatic environment.