A study of medication errors during the prescription stage in the pediatric critical care services of a secondary-tertiary level public hospital

• Published in: BMC pediatrics Vol. 20; no. 1; p. 549
• Main Authors: Brennan-Bourdon, Lorena Michele, Vázquez-Alvarez, Alan O, Gallegos-Llamas, Jahaira, Koninckx-Cañada, Manuel, Marco-Garbayo, José Luis, Huerta-Olvera, Selene G
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.12.2020; BioMed Central; BMC
• Subjects: Anticonvulsants; Child; Critical Care; Cross-Sectional Studies; Dispensing error; Drug stores; Electrolytes; Emergency medical care; Hospitals, Public; Humans; Infant, Newborn; Intensive care; Medical errors; Medication Errors; Mexico; Patients; Pediatric critical care; Pediatric emergency; Pediatric intensive care; Pediatric research; Pediatrics; Prescription drugs; Prescription error; Prescriptions; Teaching hospitals; Working groups; Mexico; Prescription error; Pediatric critical care; Medication errors; Pediatric emergency; Dispensing error
• ISSN: 1471-2431; 1471-2431
• DOI: 10.1186/s12887-020-02442-w

Medication Errors (MEs) are considered the most common type of error in pediatric critical care services. Moreover, the ME rate in pediatric patients is up to three times higher than the rate for adults. Nevertheless, information in pediatric population is still limited, particularly in emergency/critical care practice. The purpose of this study was to describe and analyze MEs in the pediatric critical care services during the prescription stage in a Mexican secondary-tertiary level public hospital. A cross-sectional study to detect MEs was performed in all pediatric critical care services [pediatric emergency care (PEC), pediatric intensive care unit (PICU), neonatal intensive care unit (NICU), and neonatal intermediate care unit (NIMCU)] of a public teaching hospital. A pharmacist identified MEs by direct observation as the error detection method and MEs were classified according to the updated classification for medication errors by the Ruíz-Jarabo 2000 working group. Thereafter, these were subclassified in clinically relevant MEs. In 2347 prescriptions from 301 patients from all critical care services, a total of 1252 potential MEs (72%) were identified, and of these 379 were considered as clinically relevant due to their potential harm. The area with the highest number of MEs was PICU (n = 867). The ME rate was > 50% in all pediatric critical care services and PICU had the highest ME/patient index (13.1). The most frequent MEs were use of abbreviations (50.9%) and wrong speed rate of administration (11.4%), and only 11.7% of the total drugs were considered as ideal medication orders. Clinically relevant medication errors can range from mild skin reactions to severe conditions that place the patient's life at risk. The role of pharmacists through the detection and timely intervention during the prescription and other stages of the medication use process can improve drug safety in pediatric critical care services.