Establishing non-inferiority in treatment trials in psychiatry: guidelines from an Expert Consensus Meeting

Comparing the efficacy of different treatments in psychiatry is difficult for many reasons, even when they are investigated in "head-to-head" studies. A consensus meeting was, therefore, held to produce best practice guidelines for such studies. This article presents the conclusions of thi...

Full description

Saved in:
Bibliographic Details
Published inJournal of psychopharmacology (Oxford) Vol. 22; no. 4; p. 409
Main Authors Nutt, D, Allgulander, C, Lecrubier, Y, Peters, T, Wittchen, U
Format Journal Article
LanguageEnglish
Published United States 01.06.2008
Subjects
Antidepressive Agents - adverse effects
Antidepressive Agents - therapeutic use
Anxiety Disorders - diagnosis
Anxiety Disorders - drug therapy
Consensus Development Conferences as Topic
Cyclohexanols - adverse effects
Cyclohexanols - therapeutic use
Duloxetine Hydrochloride
Evidence-Based Medicine
Humans
Practice Guidelines as Topic
Randomized Controlled Trials as Topic
Serotonin Uptake Inhibitors - adverse effects
Serotonin Uptake Inhibitors - therapeutic use
Thiophenes - adverse effects
Thiophenes - therapeutic use
Venlafaxine Hydrochloride
Online AccessGet more information

Cover

More Information
Summary:Comparing the efficacy of different treatments in psychiatry is difficult for many reasons, even when they are investigated in "head-to-head" studies. A consensus meeting was, therefore, held to produce best practice guidelines for such studies. This article presents the conclusions of this consensus and illustrates it using published data in the field of antidepressant treatment of generalized anxiety disorder.
ISSN:0269-8811
DOI:10.1177/0269881108091068