Association between air pollution and type 2 diabetes: an updated review of the literature

Air pollution and type 2 diabetes mellitus (T2DM) are critical public health issues worldwide. A large number of epidemiological studies have highlighted the adverse effects of air pollution on diabetes, and include risk profiles for different exposure durations, study design types, subgroup populat...

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Published inTherapeutic Advances in Endocrinology and Metabolism Vol. 10; p. 2042018819897046
Main Authors Li, Yongze, Xu, Lu, Shan, Zhongyan, Teng, Weiping, Han, Cheng
Format Book Review Journal Article
LanguageEnglish
Published London, England SAGE Publications 2019
Sage Publications Ltd
SAGE Publishing
Subjects
Air pollution
Air pollution effects
Biomarkers
Chemical pollution
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Endoplasmic reticulum
Environmental risk
Epidemiology
Exposure
Health risks
Insulin resistance
Literature reviews
Organic chemistry
Outdoor air quality
Oxidative stress
Pollutants
Pollution
Pollution effects
Population studies
Public health
Review
Risk assessment
Subgroups
type 2 diabetes mellitus
air pollution
fine particulate matter
insulin resistance
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Summary:Air pollution and type 2 diabetes mellitus (T2DM) are critical public health issues worldwide. A large number of epidemiological studies have highlighted the adverse effects of air pollution on diabetes, and include risk profiles for different exposure durations, study design types, subgroup populations, and effects of air pollution components. We researched PubMed, Google Scholar, and Web of Science to identify studies on the association between air pollution and T2DM from January 2009 to January 2019. The aim of this review is to provide a brief overview of epidemiological and experimental studies on air pollution associated with T2DM from the latest research, which may provide practical information about this relationship and possible mechanisms. Current cumulative evidence appears to suggest that T2DM-related biomarkers increase with increasing exposure duration and concentration of air pollutants. The chemical constituents of the air pollutant mixture may affect T2DM to varying degrees. The suggested mechanisms whereby air pollutants induce T2DM include increased inflammation, oxidative stress, and endoplasmic reticulum stress.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:2042-0188
2042-0196
DOI:10.1177/2042018819897046