Severe dyspnea and uncontrolled seizures following meperfluthrin poisoning: a case report

• Published in: BMC pediatrics Vol. 21; no. 1; pp. 51 - 6
• Main Authors: Zheng, Shengkun, Zhang, Shengxin, Hong, Shaoxian, Lou, Qing
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 25.01.2021; BioMed Central; BMC
• Subjects: Auscultation; Bronchoscopy; Case Report; Case reports; Case studies; Causes of; Child; Childrens health; Complications and side effects; Cyanosis; Diagnosis; Dyspnea; Edema; Health aspects; Heimlich maneuver; Hospitalization; Insecticides; Lungs; Meperfluthrin; Mosquitoes; Pediatric emergencies; Pediatric research; Pediatrics; Pneumonia; Poisoning; Preschool children; Seizures; Seizures (Medicine); Shortness of breath; China; Meperfluthrin; Poisoning; Dyspnea; Child; Seizures
• ISSN: 1471-2431; 1471-2431
• DOI: 10.1186/s12887-021-02509-2

Meperfluthrin is a novel sanitary cyhalothrin insecticide invented in China and has increasingly been used to produce liquid mosquito repellents. Oral meperfluthrin poisoning in human has rarely been reported. Here, we reported a case of meperfluthrin poisoning by ingestion of a meperfluthrin-based liquid mosquito repellent in a 16-month-old infant. A 16-month-old boy with a history of accident ingestion of meperfluthrin was admitted to our hospital's emergency department. He exhibited severe dyspnea, and lung radiograph showed multiple patchy and cord-like high-density shadows bilaterally in a short time. He also suffered 35 min of seizures which were finally controlled by the intravenous infusion of propofol. He was diagnosed with meperfluthrin poisoning, status epilepticus and severe pneumonia. After treated with methylprednisolone, aerosolized beclomethasone dipropionate, anti-infection, and some critical supportive therapy, the patient was in good health and showed no symptoms during 12 months of follow-up. Meperfluthrin poisoning is rare. Oral meperfluthrin poisoning shows neurotoxic effects and pulmonary toxicity. Controlling seizures rapidly and ensuring an adequate oxygen supply are critical to the successful treatment.