Recent Advances and the Mechanism of Astaxanthin in Ophthalmological Diseases

Astaxanthin (AST) is a naturally occurring carotenoid that has strong antioxidant, anti-inflammatory, and antiapoptosis effects and is used for the prevention of cancer. There is growing evidence that AST has multiple protective effects against various eye diseases. This article reviews the function...

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Bibliographic Details
Published inJournal of ophthalmology Vol. 2022; pp. 1 - 11
Main Authors Yang, Ming, Wang, Yanling
Format Journal Article
LanguageEnglish
Published United States Hindawi 20.05.2022
John Wiley & Sons, Inc
Wiley
Subjects
Antioxidants
Apoptosis
Binding sites
Carotenoids
Chronic fatigue syndrome
Cytokines
Diabetes
Diabetic retinopathy
Dietary supplements
Disease prevention
Eye diseases
Flow velocity
Free radicals
Functional foods
Gene expression
Inflammation
Kinases
Lipids
Macular degeneration
Oxidation
Oxidative stress
Physiology
Prevention
Proteins
Review
Tumor necrosis factor-TNF
Type 2 diabetes
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Summary:Astaxanthin (AST) is a naturally occurring carotenoid that has strong antioxidant, anti-inflammatory, and antiapoptosis effects and is used for the prevention of cancer. There is growing evidence that AST has multiple protective effects against various eye diseases. This article reviews the function and the potential mechanism of AST in dry eye syndrome, keratitis, cataract, diabetic retinopathy, age-related macular degeneration, high intraocular pressure, and other ocular diseases. It provides a theoretical basis for the clinical application of AST as a potential nutraceutical.
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Academic Editor: Shigeru Honda
ISSN:2090-004X
2090-0058
DOI:10.1155/2022/8071406