Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes
The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CK...
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| Published in | Kidney international Vol. 87; no. 1; pp. 20 - 30 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.01.2015
Elsevier Limited |
| Subjects | |
| Online Access | Get full text |
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| Abstract | The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin–angiotensin–aldosterone system; and lipid management. |
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| AbstractList | The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management. The incidence and prevalence of diabetes mellitus (DM) continue to grow dramatically throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management. The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management.The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management. |
| Author | Wanner, Christoph Molitch, Mark E. Mogensen, Carl E. Flyvbjerg, Allan Adler, Amanda I. Nelson, Robert G. So, Wing-Yee Wheeler, David C. de Zeeuw, Dick Kasiske, Bertram L. |
| AuthorAffiliation | 2 Institute of Metabolic Science, Addenbrooke’s Hospitals, Cambridge, United Kingdom 6 University Hospital of Würzburg, Würzburg, Germany 7 Hennepin County Medical Center, Minneapolis, Minnesota, USA 10 Aarhus University Hospital and Aarhus University, Aarhus, Denmark 5 Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People’s Republic of China 8 University College London, London, United Kingdom 1 Northwestern University, Chicago, Illinois, USA 3 Aarhus University, Aarhus C, Denmark 9 University Medical Center Groningen, Groningen, The Netherlands 4 National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, United States |
| AuthorAffiliation_xml | – name: 3 Aarhus University, Aarhus C, Denmark – name: 8 University College London, London, United Kingdom – name: 9 University Medical Center Groningen, Groningen, The Netherlands – name: 5 Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People’s Republic of China – name: 10 Aarhus University Hospital and Aarhus University, Aarhus, Denmark – name: 1 Northwestern University, Chicago, Illinois, USA – name: 2 Institute of Metabolic Science, Addenbrooke’s Hospitals, Cambridge, United Kingdom – name: 7 Hennepin County Medical Center, Minneapolis, Minnesota, USA – name: 6 University Hospital of Würzburg, Würzburg, Germany – name: 4 National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, United States |
| Author_xml | – sequence: 1 givenname: Mark E. surname: Molitch fullname: Molitch, Mark E. email: molitch@northwestern.edu organization: Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA – sequence: 2 givenname: Amanda I. surname: Adler fullname: Adler, Amanda I. organization: Institute of Metabolic Science, Addenbrooke’s Hospitals, Cambridge, UK – sequence: 3 givenname: Allan surname: Flyvbjerg fullname: Flyvbjerg, Allan organization: Aarhus University, Aarhus C, Denmark – sequence: 4 givenname: Robert G. surname: Nelson fullname: Nelson, Robert G. organization: National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA – sequence: 5 givenname: Wing-Yee surname: So fullname: So, Wing-Yee organization: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People’s Republic of China – sequence: 6 givenname: Christoph surname: Wanner fullname: Wanner, Christoph organization: University Hospital of Würzburg, Würzburg, Germany – sequence: 7 givenname: Bertram L. surname: Kasiske fullname: Kasiske, Bertram L. organization: Hennepin County Medical Center, Minneapolis, Minnesota, USA – sequence: 8 givenname: David C. surname: Wheeler fullname: Wheeler, David C. organization: University College London, London, UK – sequence: 9 givenname: Dick surname: de Zeeuw fullname: de Zeeuw, Dick organization: University Medical Center Groningen, Groningen, The Netherlands – sequence: 10 givenname: Carl E. surname: Mogensen fullname: Mogensen, Carl E. organization: Aarhus University Hospital and Aarhus University, Aarhus, Denmark |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24786708$$D View this record in MEDLINE/PubMed |
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| Copyright | 2015 International Society of Nephrology Copyright Nature Publishing Group Jan 2015 |
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| Keywords | diabetic kidney disease albuminuria blood pressure lipid management glycemic control |
| Language | English |
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| Snippet | The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM).... The incidence and prevalence of diabetes mellitus (DM) continue to grow dramatically throughout the world, due primarily to the increase in type 2 DM (T2DM).... |
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| SubjectTerms | albuminuria Albuminuria - etiology blood pressure diabetic kidney disease Diabetic Nephropathies - complications Diabetic Nephropathies - diagnosis Diabetic Nephropathies - therapy Disease Progression glycemic control Humans Hyperglycemia - etiology Hypertension - etiology lipid management |
| Title | Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes |
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