Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes

• Published in: Kidney international Vol. 87; no. 1; pp. 20 - 30
• Main Authors: Molitch, Mark E., Adler, Amanda I., Flyvbjerg, Allan, Nelson, Robert G., So, Wing-Yee, Wanner, Christoph, Kasiske, Bertram L., Wheeler, David C., de Zeeuw, Dick, Mogensen, Carl E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2015; Elsevier Limited
• Subjects: albuminuria; Albuminuria - etiology; blood pressure; diabetic kidney disease; Diabetic Nephropathies - complications; Diabetic Nephropathies - diagnosis; Diabetic Nephropathies - therapy; Disease Progression; glycemic control; Humans; Hyperglycemia - etiology; Hypertension - etiology; lipid management; diabetic kidney disease; albuminuria; blood pressure; lipid management; glycemic control
• ISSN: 0085-2538; 1523-1755; 1523-1755
• DOI: 10.1038/ki.2014.128

The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin–angiotensin–aldosterone system; and lipid management.