Ferret Hepatitis E Virus Infection in Japan

We examined 85 fecal samples from pet ferrets in 10 animal hospitals in Japan for the detection of ferret hepatitis E virus (HEV) RNA. We found that 6 (7.1%) of the samples were positive for ferret HEV RNA. Phylogenetic analysis based on the partial ORF1 indicated that these ferret HEV strains were...

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Bibliographic Details
Published inJapanese Journal of Infectious Diseases Vol. 68; no. 1; pp. 60 - 62
Main Authors Li, Tian-Cheng, Yonemitsu, Kenzo, Terada, Yutaka, Takeda, Naokazu, Takaji, Wakita, Maeda, Ken
Format Journal Article
LanguageEnglish
Published Japan National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee 01.01.2015
Subjects
ALT
Animals
Cluster Analysis
Feces - virology
Female
ferret hepatitis E virus
Ferrets
Genetic Variation
Genotype
Hepatitis E - epidemiology
Hepatitis E - veterinary
Hepatitis E - virology
Hepatitis E virus - isolation & purification
Hospitals, Animal
Japan - epidemiology
Male
Molecular Epidemiology
Molecular Sequence Data
pathogenicity
pet
Phylogeny
RNA, Viral - genetics
RNA, Viral - isolation & purification
Sequence Analysis, DNA
Sequence Homology
Japan
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Summary:We examined 85 fecal samples from pet ferrets in 10 animal hospitals in Japan for the detection of ferret hepatitis E virus (HEV) RNA. We found that 6 (7.1%) of the samples were positive for ferret HEV RNA. Phylogenetic analysis based on the partial ORF1 indicated that these ferret HEV strains were clearly separated from the Netherlands strains and were divided into 2 distinct clusters. These results suggest that ferret HEV is genetically diverse, and since ferrets are not indigenous to Japan, ferret HEV has been introduced into Japan through importation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1344-6304
1884-2836
1884-2836
DOI:10.7883/yoken.JJID.2014.169