心房颤动与痴呆

研究发现，心房颤动（简称房颤）是痴呆相关的高危独立因素。心房颤动易引起心房产生血栓，栓子脱落后，并发体循环栓塞的风险极大。当栓子堵住脑部小血管时，损害足够容量的脑组织，就会引起血管性痴呆。因此，如果可以研究清楚二者之间的发病机制和危险因素，通过治疗阻断这一机制，并减少二者发生的危险因素，就会减少由心房颤动引发的痴呆。然而，抗凝不足或过度抗凝都会导致痴呆。...

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Bibliographic Details
Published in中国卒中杂志 Vol. 12; no. 2; pp. 188 - 191
Main Author 武崇光 柴琴琴 宋彦丽 林杰 武一平
Format Journal Article
LanguageChinese
Published 1056002 邯郸邯郸市第一医院神经内一科 2017
河北工程大学医学院%1056002,邯郸邯郸市第一医院神经内一科
Subjects
心房颤动
痴呆
综述
阿尔茨海默症
Alzheimer’s disease
Atrial ifbrillation
心房颤动
阿尔茨海默症
综述
Review
痴呆
Dementia
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Summary:研究发现，心房颤动（简称房颤）是痴呆相关的高危独立因素。心房颤动易引起心房产生血栓，栓子脱落后，并发体循环栓塞的风险极大。当栓子堵住脑部小血管时，损害足够容量的脑组织，就会引起血管性痴呆。因此，如果可以研究清楚二者之间的发病机制和危险因素，通过治疗阻断这一机制，并减少二者发生的危险因素，就会减少由心房颤动引发的痴呆。然而，抗凝不足或过度抗凝都会导致痴呆。
Bibliography:11-5434/R
Atrial ifbrillation; Dementia; Alzheimer’s disease; Review
Study found that atrial ifbrillation was an independent risk factor for dementia. Atrial ifbrillation can lead to atrial thrombus formation and high risk of concurrent systemic embolism after falling off emboli. When the embolus blocked small blood vessels in the brain, damage of sufifcient capacity of the brain tissue can cause vascular dementia. Therefore, if the pathogenesis mechanism and risk factors of the two could be understood, we could block this mechanism by treatment and reduce risk factors so as to reduce dementia caused by atrial ifbrillation. However, under or over anticoagulation can lead to dementia.
WU Chong-Guang, CHAI Qin-Qin, SONG Yan-Li, LIN Jie, WU Yi-Ping. （The First Hospital of Handan, Handan 056002, China）
ISSN:1673-5765
DOI:10.3969/j.issn.1673-5765.2017.02.019