踝肱指数的变化与新发不良心脑血管事件的关系

目的探讨踝肱指数（ABI）的变化与新发不良心脑血管事件的关系。方法2011年5月—8月，采用整群抽样法对贵阳市云岩区4160例40岁及以上常住居民进行基线调查，测定ABI并收集体格检查、血生化检测及病史资料，于2014年7月—12月对该人群进行随访调查，平均随访（39.29±1.47）个月。根据随访与入选时相比ABI变化情况（ΔABI）将入选人群分为3组：ΔABI＞0.15组，-0.15≤ΔABI≤0.15组，ΔABI＜-0.15组。比较3组人群在随访期间新发不良心脑血管事件情况，并分析影响不良心脑血管事件的危险因素。结果3年后共完成随访3220例，随访完成率为77.4%。3220例在随访期间...

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Bibliographic Details
Published in天津医药 Vol. 44; no. 8; pp. 959 - 962
Main Author 周皖舒;彭年春;时立新;张巧;胡颖;徐淑静;张淼;张松
Format Journal Article
LanguageChinese
Published 贵州医科大学附属医院内分泌代谢病科 邮编550004 2016
Subjects
心脑血管事件;踝肱指数;危险因素
cardiovascular events
risk factors
踝肱指数
危险因素
心脑血管事件
ankle brachial index
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ISSN0253-9896
DOI10.11958/20160120

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Summary:目的探讨踝肱指数（ABI）的变化与新发不良心脑血管事件的关系。方法2011年5月—8月，采用整群抽样法对贵阳市云岩区4160例40岁及以上常住居民进行基线调查，测定ABI并收集体格检查、血生化检测及病史资料，于2014年7月—12月对该人群进行随访调查，平均随访（39.29±1.47）个月。根据随访与入选时相比ABI变化情况（ΔABI）将入选人群分为3组：ΔABI＞0.15组，-0.15≤ΔABI≤0.15组，ΔABI＜-0.15组。比较3组人群在随访期间新发不良心脑血管事件情况，并分析影响不良心脑血管事件的危险因素。结果3年后共完成随访3220例，随访完成率为77.4%。3220例在随访期间共新发不良心脑血管事件82例（2.5%）。其中，ΔABI＜-0.15组不良心脑血管事件发生率较-0.15≤ΔABI≤0.15组升高（8.3%vs.2.4%，P＜0.0167）。Logistic回归分析表明，年龄高、高血压史和ΔABI＜-0.15均为不良心脑血管事件的危险因素，运动是保护因素。结论ΔABI＜-0.15者不良心脑血管事件的发生风险增加，ΔABI可作为不良心脑血管事件的监测手段，对判断不良心脑血管事件的发生有一定的预测价值。
Bibliography:cardiovascular events; ankle brachial index; risk factors
Objective To investigate the relationship between changes of ankle brachial index (ABI) and adverse cardiovascular events. Methods Baseline survey was conducted in 4 160 forty-year-old or older citizens living in Yunyan District of Guiyang City from May to August of 2011, which was in the way of cluster sampling to obtain their ABI and to collect information related to physical and blood biochemical examination and disease history. These citizens were conducted a follow-up survey for (39.29±1.47) months from July to December of 2014. Based on the change of ABI (ΔABI) from initial survey to follow-up survey, participants were subsequently divided into three groups: ΔABI>0.15 group, -0.15 ≤ ΔABI ≤0.15 group and ΔABI<-0.15 group. The adverse cardiovascular events during follow-up survey were compared between three groups. The risk factors affecting the adverse cardiovascular events were analyzed. Results Follow-up surveys were completed in 3 220 citi
ISSN:0253-9896
DOI:10.11958/20160120