I 2 -catalyzed synthesis of 3-aminopyrrole with homopropargylic amines and nitrosoarenes

• Published in: Chemical communications (Cambridge, England) Vol. 60; no. 27; pp. 3701 - 3704
• Main Authors: Qin, Jiaze, Jiang, Shixuan, Luo, Xiaofeng, Wang, Tianqiang, Liu, Peihua, Yuan, Bingxiang, Yan, Rulong
• Format: Journal Article
• Language: English
• Published: England 28.03.2024

The synthesis of 3-aminopyrrole using the amination reagent nitrosoarenes and homopropargylic amines catalyzed by I through cyclization and amination has been developed. This protocol features excellent functional group tolerance and mild reaction conditions, yielding 3-aminopyrroles in moderate to...