Age- and sex-related differences of muscle cross-sectional area in iliocapsularis: a cross-sectional study

• Published in: BMC geriatrics Vol. 22; no. 1; p. 435
• Main Authors: Yagi, Masahide, Taniguchi, Masashi, Tateuchi, Hiroshige, Hirono, Tetsuya, Fukumoto, Yoshihiro, Yamagata, Momoko, Nakai, Ryusuke, Yamada, Yosuke, Kimura, Misaka, Ichihashi, Noriaki
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.05.2022; BioMed Central; BMC
• Subjects: Age; Age factors in disease; Age-related difference; Aged; Analysis; Atrophy; Care and treatment; Cross-Sectional Studies; Diagnosis; Female; Gender differences; Geriatrics; Hip joint; Humans; Iliocapsularis; Magnetic Resonance Imaging; Male; Methods; Muscle function; Muscle, Skeletal - diagnostic imaging; Muscle, Skeletal - pathology; Muscles; Older people; Quadriceps muscle; Quadriceps Muscle - diagnostic imaging; Risk factors; Sex; Sex Characteristics; Sex differences; Sex factors in disease; Sex-related difference; Variance analysis; Womens health; Japan; Germany; Atrophy; Iliocapsularis; Age-related difference; Sex-related difference
• ISSN: 1471-2318; 1471-2318
• DOI: 10.1186/s12877-022-03127-y

This study aimed to determine in how many individuals the iliocapsularis muscle (IC) could be identified on magnetic resonance imaging (MRI) and whether age and sex are associated with the cross-sectional area (CSA) of the IC. Thirty-seven healthy younger adults and 40 healthy older adults were assigned to four groups: 1) 20 younger men; 2) 17 younger women; 3) 20 older men; and 4) 20 older women. The CSAs of the IC, IP, the rectus femoris (RF) and the quadriceps (QUAD) were quantified on an axial MRI. The number of individuals with the identified IC was n = 17 (85.0%) of 20 younger men, n = 15 (88.2%) of 17 younger women, n = 18 (90.0%) of 20 older men, and 19 (95.0%) of 20 older women. Our results showed the main effect of sex, but not age, in the CSA of the IC. The men-groups had larger CSA of the IC than the women-groups; however, no difference in CSA of the IC was found between the younger and older groups. Meanwhile, the main effects of age and sex were found for the IP, RF, and QUAD; thus, younger or men groups have larger CSAs of the three muscles than the older or women groups. The IC muscle can be discriminated in 85% - 95% of healthy individuals. Although sex and age are associated with the CSA of lower-limb muscles other than the IC, only sex is associated with the CSA of the IC.